5582-12-7

Basic information

• Product Name: α-aminomethyl cinnamyl alcohol
• Synonyms: α-aminomethyl cinnamyl alcohol
• CAS NO: 5582-12-7
• Molecular Weight: 163.219
• Mol File: 5582-12-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-aminomethyl cinnamyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: α-aminomethyl cinnamyl alcohol(5582-12-7)
• EPA Substance Registry System: α-aminomethyl cinnamyl alcohol(5582-12-7)

Safety Data

• Hazardous Substances Data: 5582-12-7(Hazardous Substances Data)

Upstream product

• 61912-03-6 2-hydroxy-4-phenyl-3-butenenitrile 
• 104-55-2 3-phenyl-propenal 

Relevant articles and documents

Aminoalcohol neuraminidase inhibitors, and preparation method thereof

The invention discloses aminoalcohol neuraminidase inhibitors, and a preparation method thereof. The method concretely comprises the following steps: 1, reacting cinnamaldehyde, lithium perchlorate LiClO4.3H2O and trimethylsilyl cyanide (TMSCN) to obtain cyan analog; 2, reducing the cyan analog under the action of a reducing agent and an additive in order to obtain hydroxyl-substituted amino compounds; 3, reacting the hydroxyl-substituted amino compounds with acyl chloride under an alkaline condition to obtain one neuraminidase inhibitor; and 4, reacting the hydroxyl-substituted amino compounds with substituted benzyl bromide under an alkaline condition to obtain another one neuraminidase inhibitor with another structure. The compounds synthesized in the invention have novel structures, and have good neuraminidase activity.