558466-12-9 Usage
General Description
3-Pyridinethiol,6-chloro-(9CI) is a chemical compound with the molecular formula C5H4ClNS. It is a derivative of pyridine and contains both a thiol group and a chlorine atom. 3-Pyridinethiol,6-chloro-(9CI) is commonly used in organic synthesis and medicinal chemistry, often as a building block for the synthesis of more complex molecules. It is known for its strong odor and is considered to be a hazardous substance, with potential health hazards including skin and eye irritation, as well as harmful effects if ingested or inhaled. Additionally, this compound has been studied for its potential biological and pharmacological properties, including its potential as an anti-inflammatory and anti-cancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 558466-12-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,8,4,6 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 558466-12:
(8*5)+(7*5)+(6*8)+(5*4)+(4*6)+(3*6)+(2*1)+(1*2)=189
189 % 10 = 9
So 558466-12-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H4ClNS/c6-5-2-1-4(8)3-7-5/h1-3,8H
558466-12-9Relevant articles and documents
PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE
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Paragraph 0509; 0511-0512, (2021/09/26)
The present invention provides, in part, novel small molecule inhibitors of PHD, having a structure according to Formula (A), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for treatment of diseases including heart ( e.g. ischemic heart disease, congestive heart failure, and valvular heart disease), lung (e.g., acute lung injury, pulmonary hypertension, pulmonary fibrosis, and chronic obstructive pulmonary disease), liver (e.g. acute liver failure and liver fibrosis and cirrhosis), and kidney (e.g. acute kidney injury and chronic kidney disease) disease.
BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS
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Page 131, (2010/02/08)
Provided are novel compounds having an inhibitory activity against production or secretion of β-amyloid protein. They embrace compounds represented by the following formula (1): and capable of being replaced with a variety of substituents; and salts thereof, and solvates of any one of them.
