56263-57-1

Basic information

• Product Name: tert-butyl 4-fluorobenzoperoxoate
• Synonyms: tert-butyl 4-fluorobenzoperoxoate
• CAS NO: 56263-57-1
• Molecular Weight: 212.221
• Mol File: 56263-57-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-fluorobenzoperoxoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-fluorobenzoperoxoate(56263-57-1)
• EPA Substance Registry System: tert-butyl 4-fluorobenzoperoxoate(56263-57-1)

Safety Data

• Hazardous Substances Data: 56263-57-1(Hazardous Substances Data)

Upstream product

• 75-91-2 tert.-butylhydroperoxide 
• 459-56-3 4-fluorobenzylic alcohol 
• 352-32-9 p-fluorotoluene 
• 459-22-3 4-fluorophenylacetonitrile 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 1345403-77-1 cyclohex-2-en-1-yl 4-fluorobenzoate 
• 68175-34-8 1-(tert-butyl)-4-(prop-1-en-1-yl)benzene 

Relevant articles and documents

Temperature-controlled solvent-free selective synthesis of tert-butyl peresters or acids from benzyl cyanides in the presence of the TBHP/Cu(OAc)2 system

Solvent-free room temperature synthesis of tert-butyl peresters was achieved via copper-catalyzed oxidative-coupling of benzyl cyanides with tert-butyl hydroperoxide in short reaction times. Various derivatives of tert-butyl peresters were synthesized by this pathway in good to excellent yields. Further investigation revealed that the above-mentioned protocol is effective for the synthesis of benzoic acid derivatives when the reaction is conducted at 80?°C, under the same reaction conditions.

Microfluidic Synthesis of tert-Butyl Peresters via KI-Catalyzed Oxidative Coupling of Methyl Arenes and tert-Butyl Hydroperoxide

A green and efficient organic-aqueous two-phase reaction route for the synthesis of tert-butyl peresters by KI-catalyzed C-H oxidation of methyl arenes in a microfluidic chip reactor has been developed. Moreover, a series of tert-butyl perester products were obtained in moderate to good yields under metal-free conditions. A scale-up continuous flow system was constructed to verify the application of this method.

Synthesis of tert-butyl peresters from aldehydes by Bu4NI- catalyzed metal-free oxidation and its combination with the Kharasch-Sosnovsky reaction

A new tert-butyl peresters synthesis directly from aldehydes and TBHP was developed via Bu4NI-catalyzed aldehyde C-H oxidation. Mechanistic studies suggest that the protocol proceeds via a radical process. Combining the method with the Kharasch-Sosnovsky reaction offers a practical approach for the synthesis of allylic esters from simple aldehydes and alkenes via a two-step one-pot procedure.