5664-49-3

Basic information

• Product Name: 1-phenyl-N,N-bis(1,3-thiazol-2-yl)methanediamine
• CAS NO: 5664-49-3
• Molecular Formula: C₁₃H₁₂N₄S₂
• Molecular Weight: 288.397
• Mol File: 5664-49-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 485.8°Cat760mmHg
• Flash Point: 247.6°C
• Density: 1.444g/cm³
• CAS DataBase Reference: 1-phenyl-N,N-bis(1,3-thiazol-2-yl)methanediamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-N,N-bis(1,3-thiazol-2-yl)methanediamine(5664-49-3)
• EPA Substance Registry System: 1-phenyl-N,N-bis(1,3-thiazol-2-yl)methanediamine(5664-49-3)

Safety Data

• Hazardous Substances Data: 5664-49-3(Hazardous Substances Data)

Usage

Chemical Structure

Two thiazole rings and a phenyl group attached to a methanediamine backbone

Primary Use

Corrosion inhibitor for copper

Industrial Applications

Cooling water systems, oilfield operations

Function

Forms a protective film on copper surfaces to prevent corrosion and extend equipment lifespan

Properties

High thermal stability, effective at low concentrations

Upstream product

• 96-50-4 2-thiazolylamine 
• 100-52-7 benzaldehyde 
• 67-56-1 methanol 

Downstream Products

• 77655-27-7 2-fenil-3-(2-tiazolil)-4-tiazolidinone 
• 96-50-4 2-thiazolylamine 
• 13243-76-0 benzylidene-1,3-thiazol-2-yl-amine 

Relevant articles and documents

NHC-Catalyzed Aza-Benzoin Condensation of N, N′-Dipyridin-2-yl Aminals with Aldehydes

α-Amino ketones are useful compounds because of their synthetic utility and bioactivities. After observing the ability of N,N′-dipyridin-2-yl aminals to form imines in situ, the synthesis of α-amino ketones using N,N′-dipyridin-2-yl aminals was proposed.

CONDENSATION REACTIONS BETWEEN AROMATIC ALDEHYDES AND SOME HETEROCYCLIC AROMATIC AMINES

1,1-Diamino derivatives are obtained by means of reactions between 2-aminothiazole and aromatic aldehydes carried out in methanol (and in dimethyl sulphoxide).The reaction of amine with the C=N of imine occurs without catalyst and is an easier process than its addition to C=O.This behaviour is also displayed by a number of aromatic heterocycles and homocyclic amines and may be explained by considering the activating effect of the electron-withdrawing group present in the imine moiety.