566885-71-0

Basic information

• Product Name: Benzamide, 4-(bromomethyl)-N-ethyl-
• CAS NO: 566885-71-0
• Molecular Formula: C10H12BrNO
• Molecular Weight: 242.115
• Mol File: 566885-71-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-(bromomethyl)-N-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-(bromomethyl)-N-ethyl-(566885-71-0)
• EPA Substance Registry System: Benzamide, 4-(bromomethyl)-N-ethyl-(566885-71-0)

Safety Data

• Hazardous Substances Data: 566885-71-0(Hazardous Substances Data)

Upstream product

• 6232-88-8 4-bromomethylbenzoic Acid 
• 52780-16-2 4-bromomethylbenzoyl chloride 
• 75-04-7 ethylamine 

Relevant articles and documents

Discovery of novel 5-methyl-1H-pyrazole derivatives as potential antiprostate cancer agents: Design, synthesis, molecular modeling, and biological evaluation

Androgen receptor (AR) signaling functions as a core driving force for the progression of prostate cancer (PCa), and AR has been proved to be an effective therapeutic target even for castration-resistant prostate cancer (CRPC). Herein, structural modification via a fragments splicing strategy was performed based on two lead compounds T3 and 10e, leading to the discovery of a series of 5-methyl-1H-pyrazole derivatives. AR reporter gene assay revealed compounds A13 and A14 as potent AR antagonists. Some of the compounds in this series inhibited growth of PCa LNCaP cells more efficiently than enzalutamide. A13 and A14 also showed improved metabolic stability compared with 10e in human liver microsomes.