5683-30-7 Usage
Description
3-(TRIMETHYLSILYL) PROPIONIC ACID, also known as a trimethylsilyl-substituted propionic acid, is an organosilicon compound characterized by the presence of a trimethylsilyl group at the 3rd position of the propionic acid molecule. It is widely recognized for its utility as an internal reference in the field of nuclear magnetic resonance (NMR) spectroscopy, particularly for aqueous solvents such as D2O.
Uses
Used in Chemical Analysis:
3-(TRIMETHYLSILYL) PROPIONIC ACID is used as an internal reference for [providing accurate chemical shifts] in the NMR spectrum for [ensuring precise and reliable analysis of samples in aqueous solvents like D2O].
Used in Pharmaceutical Industry:
3-(TRIMETHYLSILYL) PROPIONIC ACID is used as a reference compound for [standardizing NMR measurements] in the development and quality control of pharmaceutical products [to ensure the accurate identification and quantification of active ingredients and impurities].
Used in Research and Development:
3-(TRIMETHYLSILYL) PROPIONIC ACID is used as a benchmark substance for [calibrating NMR equipment] in various research and development laboratories [to guarantee the consistency and reproducibility of experimental results].
Used in Material Science:
3-(TRIMETHYLSILYL) PROPIONIC ACID is used as a structural component for [designing and synthesizing novel organosilicon materials] in the field of material science [due to its unique properties and reactivity].
Used in Environmental Science:
3-(TRIMETHYLSILYL) PROPIONIC ACID is used as a tracer compound for [investigating the behavior and fate of organic pollutants] in the environment [owing to its distinctive characteristics and detectability in NMR analyses].
Check Digit Verification of cas no
The CAS Registry Mumber 5683-30-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,8 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5683-30:
(6*5)+(5*6)+(4*8)+(3*3)+(2*3)+(1*0)=107
107 % 10 = 7
So 5683-30-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H14O2Si/c1-9(2,3)5-4-6(7)8/h4-5H2,1-3H3,(H,7,8)
5683-30-7Relevant articles and documents
Reaction of acylsilanes with potassium cyanide: Brook rearrangement under phase-transfer catalytic conditions
Takeda, Kei,Ohnishi, Yuji
, p. 4169 - 4172 (2007/10/03)
The reactions of acylsilanes with KCN under liquid-liquid phase-transfer catalytic conditions proceeded smoothly via the Brook rearrangement to produce O-silylated cyanohydrin derivatives in excellent yields. We also found that α-cyano carbanions generate
A Regiocontrolled and Stereocontrolled Synthesis of Allylsilanes from β-Silyl Enolates
Fleming, Ian,Gil, Salvador,Sarkar, Achintya K.,Schmidlin, Tibur
, p. 3351 - 3362 (2007/10/02)
The α-lithiated diphenylphosphine oxides 3 react with methyl iodide to give the phosphine oxides 4 and 5 in a ratio 3-4:1.The corresponding reaction with aldehydes gives all four diastereomeric alcohols 7-10, which are not suitable for the synthesis of allylsilanes by a Wittig-Horner reaction.The β-dimethyl(phenyl)silyl enolates 13-15 and 25-28 react with aldehydes to give aldol products with high diastereoselectivity.The benzyl and allyl ester groups can be cleaved from these aldols to give the acids 16-18 and 29-32.The acids, in turn, can be induced to undergo dec arboxylative elimination stereospecifically either in a syn or an anti sense to give the allylsilanes 19, 20, 23, 24, 33, 34 and 39-41.A similar series of reactions can be carried out with the β-trimethylsilyl enolates 45 and 46 giving the allylsilanes 49, 50, 53 and 54.
Cyclic Olefins by Anodic Oxidation of β-(Trimethylsilyl)carboxylic Acids. - β-(Trimethylsilyl)acrylic Acid Derivatives as Acetylene Equivalents in Diels-Alder Reactions
Hermeling, Dieter,Schaefer, Hans J.
, p. 1151 - 1158 (2007/10/02)
Trimethylsilyl-substituted dienophiles 1, 2, and 4 react with dienes 6-14 in 66-100percent yields to give β-trimethylsilyl-substituted carboxylic acids 15-25, some of which are hydrogenated to 26-31.These are decarboxylated-desilylated to cyclic olefins 35-47 by Non-Kolbe electrolysis in 45-91percent yields.The dienophiles 1, 2, and 4 are thus suitable acetylene equivalents for Diels-Alder reactions.
