862693-78-5

Basic information

• Product Name: N-[1-(R)-(1-cyanocyclopropylcarbamoyl)-2-(trimethylsilanyl)ethyl]-3-boronic benzamid
• Synonyms: N-[1-(R)-(1-cyanocyclopropylcarbamoyl)-2-(trimethylsilanyl)ethyl]-3-boronic benzamid
• CAS NO: 862693-78-5
• Molecular Weight: 373.292
• Mol File: 862693-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[1-(R)-(1-cyanocyclopropylcarbamoyl)-2-(trimethylsilanyl)ethyl]-3-boronic benzamid(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-(R)-(1-cyanocyclopropylcarbamoyl)-2-(trimethylsilanyl)ethyl]-3-boronic benzamid(862693-78-5)
• EPA Substance Registry System: N-[1-(R)-(1-cyanocyclopropylcarbamoyl)-2-(trimethylsilanyl)ethyl]-3-boronic benzamid(862693-78-5)

Safety Data

• Hazardous Substances Data: 862693-78-5(Hazardous Substances Data)

Upstream product

• 862693-45-6 (2R,4S)-4-benzyl-3-[3-(trimethylsilanyl)-2-azidopropionyl]oxazolidin-2-one 
• 862693-44-5 (S)-4-benzyl-3-[3-(trimethyl-silanyl)propionyl]oxazolidin-2-one 
• 5683-30-7 3-trimethylsilylpropionic acid 
• 18187-31-0 3-(trimethylsilyl)propanoyl chloride 
• 25487-66-5 3-Carboxyphenylboronic acid 

Downstream Products

• 862693-75-2 3'-methoxybiphenyl-3-carboxylic acid [1-(R)-(1-cyanocyclopropyl-carbamoyl)-2-(trimethyl-silanyl)ethyl]amide 

Relevant articles and documents

SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is also directed to pharmaceutical compositions comprising these compounds and processes for preparing them. The present invention is also directed to the use of these inhibitors in combination with a therapy that causes a deleterious immune response in patients receiving the therapy.