570402-52-7

Basic information

• Product Name: 1H-Pyrrole-2,5-dicarboxylic acid, 1-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroxy-, dimethyl ester
• CAS NO: 570402-52-7
• Molecular Formula: C18H21NO8
• Molecular Weight: 379.367
• Mol File: 570402-52-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2,5-dicarboxylic acid, 1-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroxy-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2,5-dicarboxylic acid, 1-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroxy-, dimethyl ester(570402-52-7)
• EPA Substance Registry System: 1H-Pyrrole-2,5-dicarboxylic acid, 1-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroxy-, dimethyl ester(570402-52-7)

Safety Data

• Hazardous Substances Data: 570402-52-7(Hazardous Substances Data)

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 553-90-2 Dimethyl oxalate 
• 570402-50-5 dimethyl N-[2-(3,4-dimethoxyphenyl)ethyl]iminodiacetate 
• 431-03-8 dimethylglyoxal 

Downstream Products

• 475232-29-2 3-hydroxy-14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-6H-[1]benzopyrano[4',3':4,5]-pyrrolo[2,1-a]isoquinolin-6-one 
• 1352336-52-7 8,9-dihydro-14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-6-oxo-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-3-yl 2,2,2-trichloroethyl sulfate 
• 1352336-51-6 8,9-dihydro-2,11,12-trimethoxy-14-[4-methoxy-3-(methoxymethoxy)phenyl]-6-oxo-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-3-yl 2,2,2-trichloroethyl sulfate 
• 1352336-50-5 8,9-dihydro-3-hydroxy-2,11,12-trimethoxy-14-[4-methoxy-3-(methoxymethoxy)phenyl]-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-6-one 
• 1352336-44-7 sodium 3-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydro-1-(3-hydroxy-4-methoxyphenyl)-8-methoxy-4-oxo-[1]benzopyrano[3,4-b]pyrrol-7-yl sulfate 
• 1352336-49-2 3-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydro-1-(3-hydroxy-4-methoxyphenyl)-8-methoxy-4-oxo-[1]benzopyrano[3,4-b]pyrrol-7-yl 2,2,2-trichloroethyl sulfate 
• 1352336-48-1 3-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydro-8-methoxy-1-[4-methoxy-3-(methoxymethoxy)phenyl]-4-oxo-[1]benzopyrano[3,4-b]pyrrol-7-yl 2,2,2-trichloroethyl sulfate 
• 1352336-47-0 3-[2-(3,4-dimethoxyphenyl)ethyl]-7-hydroxy-8-methoxy-1-[4-methoxy-3-(methoxymethoxy)phenyl]-[1]benzopyrano[3,4-b]pyrrol-4(3H)-one 
• 1225441-65-5 2,2,2-trichloroethyl 2,11,12-trimethoxy-14-[4-methoxy-3-(methoxymethoxy)phenyl]-6-oxo-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-3-yl sulfate 
• 1225441-64-4 3-hydroxy-2,11,12-trimethoxy-14-[4-methoxy-3-(methoxymethoxy)phenyl]-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-6-one 
• 1225441-51-9 sodium 5-{3-hydroxy-2,11,12-trimethoxy-6-oxo-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-14-yl}-2-methoxyphenyl sulfate 
• 1225441-63-3 5-{3-hydroxy-2,11,12-trimethoxy-6-oxo-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-14-yl}-2-methoxyphenyl 2,2,2-trichloroethyl sulfate 
• 1225441-62-2 5-{3-benzyloxy-2,11,12-trimethoxy-6-oxo-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-14-yl}-2-methoxyphenyl 2,2,2-trichloroethyl sulfate 
• 1225441-61-1 3-benzyloxy-14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-6H-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-6-one 

Relevant articles and documents

Synthesis, structure-activity relationships, and mechanism of action of anti-HIV-1 lamellarin α 20-sulfate analogues

Lamellarin α and six different types of lamellarin α 20-sulfate analogues were synthesized and their structure-activity relationships were investigated using a single round HIV-1 vector infection assay. All lamellarin sulfates having pentacyclic lamellarin core exhibited anti-HIV-1 activity at a 10 μM concentration range regardless of the number and position of the sulfate group. On the other hand, non-sulfated lamellarin α and ring-opened lamellarin sulfate analogues did not affect HIV-1 vector infection in similar concentrations. The lamellarin sulfates utilized in this study did not exhibit unfavorable cytotoxic effect under the concentrations tested (IC50 > 100 μM). Confocal laser scanning microscopic analysis indicated that hydrophilic lamellarin sulfates were hardly incorporated in the cell. HIV-1 Env-mediated cell-cell fusion was suppressed by lamellarin sulfates. These results suggested that lamellarin sulfates have a novel anti-HIV-1 activity besides the previously reported integrase activity inhibition, possibly at a viral entry step of HIV-1 replication.

Short and flexible route to 3,4-diarylpyrrole marine alkaloids: Syntheses of permethyl storniamide A, ningalin B, and lamellarin G trimethyl ether

A highly efficient route to 3,4-diarylpyrrole marine alkaloids has been developed using Hinsberg-type pyrrole synthesis and palladium-catalyzed Suzuki cross-coupling of the 3,4-dihydroxypyrrole bis-triflate derivatives as key reactions. Based on this approach, formal syntheses of permethyl storniamide A and ningalin B, and a total synthesis of lamellarin G trimethyl ether have been achieved.