571-67-5 Usage
Description
Bryoponogonic acid is a naturally occurring compound with various biological activities, including antimicrobial and anticancer properties. It has been found to exhibit activity against a range of microorganisms and cancer cells, making it a potential candidate for pharmaceutical and industrial applications.
Uses
Used in Antimicrobial Applications:
Bryoponogonic acid is used as an antimicrobial agent for its ability to inhibit the growth of various bacteria and fungi, including A. hydrophilia, B. subtilis, L. monocytogenes, P. vulgaris, S. faecalis, C. albicans, and C. glabrata. Its broad-spectrum activity makes it a valuable tool in the fight against antibiotic-resistant infections.
Used in Anticancer Applications:
Bryoponogonic acid is used as an anticancer agent for its ability to inhibit the proliferation, migration, and invasion of MDA-MB-231 cells, a type of breast cancer cell. In vivo studies have shown that bryoponogonic acid (15 mg/kg, i.p.) can reduce tumor growth in an MDA-MB-231/GFP mouse xenograft model, demonstrating its potential as a therapeutic agent for cancer treatment.
Used in Pharmaceutical Industry:
Bryoponogonic acid is used as a key component in the development of new drugs and drug delivery systems, thanks to its antimicrobial and anticancer activities. Its unique properties make it a promising candidate for the creation of novel therapeutic agents and targeted drug delivery systems, which could improve the efficacy and safety of cancer treatments.
Used in Industrial Applications:
Bryoponogonic acid's antimicrobial properties also make it a valuable asset in various industrial applications, such as in the development of antimicrobial coatings for surfaces, water treatment systems, and food preservation. Its broad-spectrum activity and potential for customization in different applications make it a versatile compound for a wide range of uses.
Anticancer Research
Norstictic acid (NA) is a depsidone-derived metabolite common in several lichenspecies of the genera Usnea, Ramalina and Parmelia. Various biological activitieshave been reported for NA including antioxidant, antimicrobial and cytotoxic innature (White et al. 2014). Recently, Ebrahim et al. (2016) reported that administrationof NA to MDA-MB-231 cells significantly suppressed the proliferation,migration and invasion. Also, it showed minimal toxicity to non-tumorigenicMCF-10A mammary epithelial cells. They also performed molecular modelling,Z′-LYTE biochemical kinase assay and Western blot analysis, to identify c-Met asa potential macromolecular target. Further, NA treatment significantly suppressedMDA-MB-231/GFP tumour growth of a BC xenograft model in athymic nudemice. At this juncture, they concluded that lichen-derived natural products arepromising resources to discover novel c-Met inhibitors useful to control TNBC(Ebrahim et al. 2016).
Anticancer Research
Norstictic acid significantlysuppressed the proliferation,migration and invasion. It alsosignificantly suppressedMDA-MB-231/GFP tumour growthof a breast cancer xenograft modelin athymic nude miceEbrahimet al. (2016)
Check Digit Verification of cas no
The CAS Registry Mumber 571-67-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 571-67:
(5*5)+(4*7)+(3*1)+(2*6)+(1*7)=75
75 % 10 = 5
So 571-67-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H12O9/c1-5-3-8(20)7(4-19)14-9(5)16(22)26-13-6(2)12(21)10-11(15(13)25-14)18(24)27-17(10)23/h3-4,18,20-21,24H,1-2H3
