57198-52-4

Basic information

• Product Name: 1,3-bis-(4-methoxy-benzyl)-[1,3]diazetidine-2,4-dione
• CAS NO: 57198-52-4
• Molecular Weight: 326.352
• Mol File: 57198-52-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-bis-(4-methoxy-benzyl)-[1,3]diazetidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis-(4-methoxy-benzyl)-[1,3]diazetidine-2,4-dione(57198-52-4)
• EPA Substance Registry System: 1,3-bis-(4-methoxy-benzyl)-[1,3]diazetidine-2,4-dione(57198-52-4)

Safety Data

• Hazardous Substances Data: 57198-52-4(Hazardous Substances Data)

Upstream product

• 56651-60-6 4-methoxybenzyl isocyanate 
• 104-01-8 4-Methoxyphenylacetic acid 

Relevant articles and documents

Inhibition of serine proteases: Activity of 1,3-diazetidine-2,4-diones

The present work demonstrates that the 1,3-diazetidine-2,4-dione nucleus is effective as a scaffold of serine protease inhibitors. Compound 1 displayed high activity against human cathepsin G and α-chymotrypsin (0.39, 0.69 nM). Compound 6 exhibited 0.85 nM inhibition of human chymase. Compound 10 was a selective inhibitor against human neutrophil elastase.