5730-78-9 Usage
Description
4'-AMINO-BIPHENYL-4-CARBOXYLIC ACID, also known as 4-Aminobiphenyl-4'-carboxylic Acid, is an organic compound that serves as a crucial building block in the synthesis of various chemical compounds. It is characterized by its unique molecular structure, which features a biphenyl core with an amino group and a carboxylic acid functional group. This structure endows it with specific chemical properties and reactivity, making it a valuable component in the development of new pharmaceuticals and other applications.
Uses
Used in Pharmaceutical Industry:
4'-AMINO-BIPHENYL-4-CARBOXYLIC ACID is used as a building block for the synthesis of Biphenyl and biphenyl ether compounds. These compounds have the potential to block the DNA binding of the Human Papillomavirus (HPVs) E2 Protein, which plays a crucial role in the virus's replication process. By inhibiting this interaction, these compounds can be used for the development of antiviral agents that interfere with HPV replication, offering a promising therapeutic approach to combat HPV-related diseases.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4'-AMINO-BIPHENYL-4-CARBOXYLIC ACID is used as a key intermediate for the production of various biphenyl and biphenyl ether derivatives. These derivatives find applications in a wide range of industries, including pharmaceuticals, agrochemicals, and materials science. The versatility of 4'-AMINO-BIPHENYL-4-CARBOXYLIC ACID in chemical reactions allows for the creation of a diverse array of compounds with tailored properties and functions.
Used in Antiviral Research:
4'-AMINO-BIPHENYL-4-CARBOXYLIC ACID is used as a research tool for studying the mechanisms of HPV replication and the development of novel antiviral strategies. By understanding the interactions between the E2 Protein and DNA, researchers can gain insights into the design of more effective antiviral agents that target this specific interaction, potentially leading to the development of new treatments for HPV-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5730-78-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,3 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5730-78:
(6*5)+(5*7)+(4*3)+(3*0)+(2*7)+(1*8)=99
99 % 10 = 9
So 5730-78-9 is a valid CAS Registry Number.
5730-78-9Relevant articles and documents
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Berliner,Blommers
, p. 2479,2480 (1951)
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Functionalization of fatty acid mimetics for solid-phase coupling and subsequent target identification
Dittrich, Michaela,Zettl, Heiko,Schubert-Zsilavecz, Manfred
experimental part, p. 625 - 630 (2011/09/14)
Fatty acid mimetics such as pirinixic acid (PA) derivatives and 2-(phenylthio)alkanoic acid derivatives are drug-like small molecules with an interesting pharmacological profile. Previously, we have characterized PA derivatives (e.g., 1) as dual agonists
Derivatives of aminobenzoic and aminobiphenylcarboxylic acids useful as anti-cancer agents
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, (2008/06/13)
The present invention provides compounds having the formula: wherein n is0or1; R is —NH2or wherein R1and R2are independently selected from the group consisting of H, alkyl, aralkyl, heteroaralkyl, carboxy, carboxyalkyl, and carbamoyl; Q is R3C(O)— or wherein R5is selected from the group consisting of H, alkyl, aralkyl, heteroaralkyl, and carbamoylalkyl, and R3and R4are selected from the group consisting of H, alkyl, alkoxy, arylalkoxy, aralkyl, heteroaralkyl, and carbamoylalkyl; the Q—NH—(CH2)n— and the —C(O)R substituents of the compound of formula I are independently positioned ortho, meta, orpara relative to the carbon atoms that form the bond between the two phenyl groups to which said substituents are bound, with the proviso that said substituents are not both positioned ortho; and the Q—NH—(CH2)nand the —C(O)R substituents of the compound of formula II are positioned meta orpara to each other; or a biolabile ester thereof, or a pharmaceutically acceptable salt thereof. The compounds are useful for treating uPA- or uPAR-mediated disorders, e.g., tumor metastasis, tumor angiogenesis, restenosis, chronic inflammation, or corneal angiogenesis.
