5754-32-5

Basic information

• Product Name: 2-Methyl-1,3-dioxolane-2-ethanol
• Synonyms: 2-Methyl-1,3-dioxolane-2-ethanol;2-(2-methyl-1,3-dioxolan-2-yl)ethanol
• CAS NO: 5754-32-5
• Molecular Formula: C₆H₁₂O₃
• Molecular Weight: 132.16
• Mol File: 5754-32-5.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 2-Methyl-1,3-dioxolane-2-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-1,3-dioxolane-2-ethanol(5754-32-5)
• EPA Substance Registry System: 2-Methyl-1,3-dioxolane-2-ethanol(5754-32-5)

Safety Data

• Hazardous Substances Data: 5754-32-5(Hazardous Substances Data)

Usage

General Description

2-Methyl-1,3-dioxolane-2-ethanol is a chemical compound with the molecular formula C5H10O3. It is a colorless, clear liquid that is used as a solvent and as an intermediate in the synthesis of other chemicals. It is also known by the trade name "Tetrahydro-6-methyl-2H-pyran-2-ol" and is commonly used in the fragrance and flavor industry. It has a mild, fruity odor and is often used in perfumes, lotions, and other personal care products. In addition to its use in the fragrance industry, it is also used as a solvent in various industrial processes. As with any chemical, proper handling and safety precautions should be taken when working with 2-Methyl-1,3-dioxolane-2-ethanol to minimize the risk of exposure and potential health hazards.

Upstream product

• 6413-10-1 fructone 
• 7757-82-6 sodium sulfate 
• 90033-40-2 4-benzyloxy-2-butanone ethylene acetal 
• 250127-80-1 2-methyl-2-(2'-propynyloxyethyl)-1,3-dioxolane 
• 141-97-9 ethyl acetoacetate 
• 107-21-1 ethylene glycol 
• 590-90-9 1-Hydroxy-3-butanone 
• 56446-60-7 methyl (2-methyl-1,3-dioxolan-2-yl)acetate 

Downstream Products

• 37865-96-6 2-(2-bromoethyl)-2-methyl-1,3-dioxolane 
• 90033-40-2 4-benzyloxy-2-butanone ethylene acetal 
• 68039-72-5 2-methyl-2(2-acetoxyethyl)-1,3-dioxolane 
• 590-90-9 1-Hydroxy-3-butanone 
• 18871-63-1 3,3-ethylenedioxybutanal 
• 69803-55-0 1-(Diphenylphosphinyl)butan-3-one ethylene ketal 
• 791-28-6 Triphenylphosphine oxide 
• 15658-19-2 3,3-Ethylenedioxy-1-p-toluenesulfonate 
• 127600-04-8 1-(2-methyl-1,3-dioxolan-2-yl)but-3-en-2-one 
• 79012-40-1 (cyclopropylidene-2 ethyl)-2 methyl-2 dioxolanne-1,3 
• 128862-48-6 2-[(E)-3-(4-Chloro-3-methoxy-phenyl)-allyl]-2-methyl-[1,3]dioxolane 
• 55815-92-4 2-Methyl-2-((E)-3-phenyl-allyl)-[1,3]dioxolane 
• 86802-59-7 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-isopropyl ester 5-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl] ester 
• 86780-92-9 Ethyl 3,3-ethylenedioxybutyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 

Relevant articles and documents

SYNTHESIS OF HEPIALONE; PRINCIPAL COMPONENT FROM MALE SEX SCALES OF HEPIALUS CALIFORNICUS (LEPIDOPTERA)

Racemic and optically active hepialone, a new sex-pheromonal component produced by the male moth, Hepialus californicus Bvd., was synthesized and thus confirmed the structure of the pheromone as (2R)-2,3-dihydro-2-ethyl-6-methyl-4H-pyran-4-one (1).

Hydrogenation of Esters by Manganese Catalysts

The hydrogenation of esters catalyzed by a manganese complex of phosphine-aminopyridine ligand was developed. Using this protocol, a variety of (hetero)aromatic and aliphatic carboxylates including biomass-derived esters and lactones were hydrogenated to primary alcohols with 63–98% yields. The manganese catalyst was found to be active for the hydrogenation of methyl benzoate, providing benzyl alcohol with turnover numbers (TON) as high as 45,000. Investigation of catalyst intermediates indicated that the amido manganese complex was the active catalyst species for the reaction. (Figure presented.).

Synthesis of deuterated isopentyl pyrophosphates for chemo-enzymatic labelling methods: GC-EI-MS based 1,2-hydride shift in epicedrol biosynthesis

A sesquiterpene epicedrol cyclase mechanism was elucidated based on the gas chromatography coupled to electron impact mass spectrometry fragmentation data of deuterated (2H) epicedrol analogues. The chemo-enzymatic method was applied for the specific synthesis of 8-position labelled farnesyl pyrophosphate and epicedrol. EI-MS fragmentation ions compared with non-labelled and isotopic mass shift fragments suggest that the 2H of C6 migrates to the C7 position during the cyclization mechanism.

COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND/OR FIBROSIS

The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.