58526-50-4 Usage
Description
9-CIS-RETINOIC ACID METHYL ESTER, also known as a cis-Vitamin A derivative, is a chemical compound with significant potential in various applications due to its unique properties. It is characterized as a yellow oil, which indicates its lipophilic nature and potential for easy absorption through the skin or other biological membranes.
Uses
Used in Pharmaceutical Industry:
9-CIS-RETINOIC ACID METHYL ESTER is used as a therapeutic agent for the treatment of various skin disorders and conditions. Its application is based on its ability to regulate cell differentiation and growth, making it a promising candidate for treating conditions such as acne, psoriasis, and other hyperproliferative skin diseases.
Used in Cosmetic Industry:
In the cosmetic industry, 9-CIS-RETINOIC ACID METHYL ESTER is used as an active ingredient in anti-aging and skin rejuvenation products. Its application is due to its potential to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles.
Used in Research and Development:
9-CIS-RETINOIC ACID METHYL ESTER is also utilized in research and development for its potential role in modulating cellular signaling pathways and gene expression. Its application in this context is aimed at understanding its effects on various biological processes and identifying new therapeutic targets for the treatment of diseases.
Used in Nutritional Supplements:
As a derivative of Vitamin A, 9-CIS-RETINOIC ACID METHYL ESTER may be used in the development of nutritional supplements designed to support overall health and well-being. Its application in this industry is based on the essential role of Vitamin A in maintaining proper vision, immune function, and reproductive health.
Check Digit Verification of cas no
The CAS Registry Mumber 58526-50-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,5,2 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 58526-50:
(7*5)+(6*8)+(5*5)+(4*2)+(3*6)+(2*5)+(1*0)=144
144 % 10 = 4
So 58526-50-4 is a valid CAS Registry Number.
58526-50-4Relevant articles and documents
Synthesis of 9-cis-retinoic acid and C-20-[3H3C]-9-cis-retinoic acid with high specific activity
Tadikonda, Praveen K.,Lacy, James M.,Rigdon, Michael G.,Deluca, Hector F.
, p. 1 - 10 (2007/10/03)
The synthesis of 9-cis-retinoic acid starting from 2,2,6-trimethylcyclohexanone is described. The same methodology was extended for the synthesis of deuterium and tritium labeled 9-cis-retinoic acid with high specific activity (73 Ci/mmol). In this methodology, a Grignard reaction was utilized for introducing three tritium atoms simultaneously in the final synthetic steps.
Assignment of 1H and 13C NMR Spectra of Retinoic Acid Ester Isomers Observed in the Long-Wavelength UV-Induced Photostationary State
Curley, Robert W.,Fowble, John W.
, p. 707 - 709 (2007/10/02)
1H and 13C chemical shift assignments, obtained with the aid of two-dimensional hetenuclear shift correlation and double-quantum coherence 13C-INADEQUATE experiments, are reported for four retinoic acid ester isomers observed at the photostationary state.Also detailed are 1H assignments for three additional isomers obtained in insufficient amounts for 13C measurements.KEY WORDS - Retionic acid esters Isomer identification 1H-13C correlation spectra 13C-INADEQUATE experiment
NEW MASKED BUILDING BLOCK FOR ISOPRENOID POLYENE CHAIN SYNTHESIS
Mandai, T.,Iuchi, Y.,Suzuki, K.,Kawada, M.,Otera, J.
, p. 4721 - 4724 (2007/10/02)
The new building blocks 2, 3, and 4 have been effectively synthesized starting from 2-hydroxymethyl-4-phenylthio-1-butene (1a).A convenient synthesis of retinoic acid methyl ester (9) using 2 is also described.
