58584-80-8Relevant articles and documents
Synthesis, characterization and crystal structure of 2,3,6-trichloro-5- (trichloromethyl)pyridine
Zhu, Xue-Mei,Cai, Zhao-Sheng,Zhang, Huai-Hong,Sun, Ming-Zhu
, p. 110 - 112 (2014/03/21)
2,3,6-Trichloro-5-(trichloromethyl)pyridine (TCTCMP) was synthesized from 2-chloro-5-chloromethyl pyridine (CCMP) through two-steps chloridization using chlorine as chlorizating agent. Initially, 2-chloro-5-chloromethyl pyridine was chloridized for 8 h at reflux conditions in the presence of ultraviolet and transformed into 2-chloro-5-(trichloromethyl)pyridine (CTCMP), then CTCMP was chloridized for 6 h at 175 °C with WCl6 as catalyst. The product was characterized by FT-IR, NMR and elemental analysis. The crystal structure of TCTCMP was investigated using X-ray diffraction and SHELXTL97 software and the result indicated that TCTCMP crystallized in the orthorhombic system, space group Pbcm with a = 8.3100(17), b = 17.018 (3), c = 7.3160(15) A, V = 1034.6 (4) A3; Z 4.