587887-70-5

Basic information

• Product Name: Cyclohexane, (3-bromo-1-propynyl)-
• CAS NO: 587887-70-5
• Molecular Formula: C9H13Br
• Molecular Weight: 201.106
• Mol File: 587887-70-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclohexane, (3-bromo-1-propynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexane, (3-bromo-1-propynyl)-(587887-70-5)
• EPA Substance Registry System: Cyclohexane, (3-bromo-1-propynyl)-(587887-70-5)

Safety Data

• Hazardous Substances Data: 587887-70-5(Hazardous Substances Data)

Upstream product

• 931-48-6 2-cyclohexylacetylene 
• 42134-54-3 3-cyclohexyl-2-propyn-1-ol 

Downstream Products

• 56037-79-7 3-cyclohexylideneprop-2-en-1-ol 
• 581075-58-3 N-(3-cyclohehylidene-2-propenyl)-p-toluenesulfonamide 

Relevant articles and documents

Iron-Catalyzed Coupling of Propargyl Bromides and Alkyl Grignard Reagents

An iron-catalyzed Kumada-type cross-coupling reaction of propargyl halides with alkylmagnesium reagents is described. The reaction is fast, takes place in smooth conditions, tolerates several functional groups that would be able to react with the Grignard reagent, and may afford either allene or propargyl coupling derivatives. Factors involved in the observed regioselectivity have been studied.

Gold(I)-catalyzed enantioselective ring expansion of allenylcyclopropanols

(Chemical Equation Presented) The asymmetric gold(I)-catalyzed ring expansion of 1-allenylcyclopropanols is described. The method provides synthetically valuable cyclobutanones with a vinyl-substituted quaternary stereogenic center in high enantioselectivities and yields. The method shows a broad substrate scope, tolerating protected alcohols and amines, alkenes, unsaturated esters, and acetals. The reaction is easily adjustable to large-scale synthesis, leading to product formation without significant loss of selectivity or yield with only 0.5 mol% catalyst loading.