58809-73-7

Basic information

• Product Name: 2-(methylthio)propionic acid
• Synonyms: 2-(methylthio)propionic acid;Einecs 261-450-3;2-(methylthio)propanoic acid(SALTDATA: 0.25H2O 0.05H2SO4);2-methylsulfanylpropanoic acid
• CAS NO: 58809-73-7
• Molecular Formula: C₄H₈O₂S
• Molecular Weight: 120.17012
• EINECS: 261-450-3
• Mol File: 58809-73-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 218.7 °C at 760 mmHg
• Flash Point: 86.1 °C
• Appearance: /
• Density: 1.16 g/cm³
• PKA: 3.86±0.10(Predicted)
• CAS DataBase Reference: 2-(methylthio)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(methylthio)propionic acid(58809-73-7)
• EPA Substance Registry System: 2-(methylthio)propionic acid(58809-73-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 58809-73-7(Hazardous Substances Data)

Usage

General Description

2-(methylthio)propionic acid, also known as methionine sulfoxide, is a naturally occurring compound found in various foods and in the human body. It is a derivative of the amino acid methionine and is commonly used as a dietary supplement due to its antioxidant properties. This chemical has been studied for its potential health benefits, including its ability to protect cells from oxidative damage and its role in supporting liver function. It is also involved in the biosynthesis of other important compounds in the body and plays a role in various metabolic processes. Additionally, 2-(methylthio)propionic acid has been researched for its potential applications in the food industry, such as a food preservative and flavor enhancer.

InChI:InChI=1/C4H8O2S/c1-3(7-2)4(5)6/h3H,1-2H3,(H,5,6)

Upstream product

• 75-18-3 dimethylsulfide 
• 598-72-1 2-Bromopropionic acid 
• 57965-30-7 (S)-thiolactic acid 
• 74-88-4 methyl iodide 
• 79-42-5 2-mercaptopropanoic acid 
• 77-78-1 dimethyl sulfate 
• 5188-07-8 sodium thiomethoxide 
• 33178-97-1 (S)-2-(methylthio)propanoic acid 
• 40800-76-8 2-methylsulfanyl-propionic acid ethyl ester 

Downstream Products

• 98-10-2 benzenesulfonamide 
• 368-48-9 2-(trifluoromethyl)pyridine 
• 936908-43-9 N-4'-methylphenyl-2-(methylthio)propionamide 
• 33178-98-2 Methyl-L-(2-methylthio)-propionate 
• 61366-76-5 methyl β-(methylthio)propionate 

Relevant articles and documents

Novel erythromycins from a recombinant Saccharopolyspora erythraea strain NRRL 2338 pIG1: I. Fermentation, isolation and biological activity

In a previous report, a plasmid, pIG1, which contained the loading domain from the Streptomyces avermitilis polyketide synthase (PKS), promoters from Streptomyces coelicolor and the DEBS1-TE truncated PKS from Saccharopolyspora erythraea, was integrated into the S. erythraea chromosome, effectively replacing the natural erythromycin loading domain with the avermectin loading domain. In this paper, we report the feeding of short-chained fatty acids to this recombinant strain, and its parent, NRRL 2338. Both strains incorporated exogenously supplied fatty acids to produce novel, biologically active, C-13 substituted erythromycins.

SUBSTITUTED AZACYLES AS TRMP8 MODULATORS

Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides

Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.