58819-72-0

Basic information

• Product Name: 2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE&
• Synonyms: 2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE&;2,6-Dimethoxynicotinaldehyde;3-Pyridinecarboxaldehyde, 2,6-dimethoxy-;2,6-Dimethoxypyridine-3-carboxaldehyde, 2,6-Dimethoxy-3-formylpyridine;2,6-diMethoxypyridine-3-carbaldehyde;2,6-Dimethoxypyridine-3-carboxaldehyde 97%
• CAS NO: 58819-72-0
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16196
• Product Categories: Pyridine;Heterocyclic Compounds;Aldehyde;Building Blocks;C7 and C8;Heterocyclic Building Blocks;Pyridines
• Mol File: 58819-72-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 68-72 °C
• Boiling Point: 277.3 °C at 760 mmHg
• Flash Point: 121.5 °C
• Appearance: /
• Density: 1.174 g/cm³
• Vapor Pressure: 0.00457mmHg at 25°C
• Refractive Index: 1.537
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.23±0.10(Predicted)
• CAS DataBase Reference: 2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE&(CAS DataBase Reference)
• NIST Chemistry Reference: 2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE&(58819-72-0)
• EPA Substance Registry System: 2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE&(58819-72-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-41-43
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 58819-72-0(Hazardous Substances Data)

Usage

General Description

2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE is a chemical compound with the molecular formula C10H11NO3. It is a pyridine derivative and contains two methoxy groups and a carboxaldehyde functional group. 2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE& has several potential applications, including its use as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in organic synthesis as a building block for the preparation of various compounds. Additionally, 2 6-DIMETHOXYPYRIDINE-3-CARBOXALDEHYDE has been studied for its potential biological activities, making it a compound of interest in medicinal chemistry research. Overall, this chemical has diverse applications and properties that make it a valuable compound in various fields.

InChI:InChI=1/C8H9NO3/c1-11-7-4-3-6(5-10)8(9-7)12-2/h3-5H,1-2H3

Upstream product

• 40381-90-6 2,6-dichloro-3-pyridinecarbonitrile 
• 124-41-4 sodium methylate 
• 72648-12-5 2-chloro-3-(trichloromethyl)-pyridine 
• 67-56-1 methanol 

Downstream Products

• 1279088-30-0 1-(2,6-dimethoxy-pyridin-3-yl)-3-phenyl-prop-2-yn-1-ol 
• 170689-01-7 N-(2-Benzyloxy-5-{(R)-2-[(R)-1-(2,6-dimethoxy-pyridin-3-yl)-2-phenyl-ethylamino]-1-triethylsilanyloxy-ethyl}-phenyl)-methanesulfonamide 
• 934286-83-6 C₂₂H₃₁NO₄Si 
• 934286-75-6 C₂₂H₃₁NO₄Si 
• 934286-66-5 C₈H₁₀NO₂Br 
• 562840-47-5 (2,6-dimethoxypyridin-3-yl)methanol 

Relevant articles and documents

Transformations of trichloromethyl groups during reactions of 3-trichloromethylpyridines with methoxide

When methoxide ion attacks an unsubstituted 2- or 6-position of a 3-trichloromethylpyridine, a hydrogen shift leads to a methoxy-substituted 3-dichloromethylpyridine. Further reaction of the dichloromethyl group with methoxide gives the corresponding acetal. This type of reaction has been applied to several chlorinated 3-trichloromethylpyridines and to 3- trichloromethylpyridine itself; a convenient synthesis of the latter is described.