72648-12-5

Basic information

• Product Name: 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE
• Synonyms: AKOS BBS-00001893;2-CHLORO-3-TRICHLOROMETHYLPYRIDINE
• CAS NO: 72648-12-5
• Molecular Formula: C₆H₃Cl₄N
• Molecular Weight: 230.91
• Mol File: 72648-12-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 291.5 °C at 760 mmHg
• Flash Point: 157.7 °C
• Appearance: /
• Density: 1.582 g/cm³
• Vapor Pressure: 0.0034mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE(72648-12-5)
• EPA Substance Registry System: 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE(72648-12-5)

Safety Data

• Hazardous Substances Data: 72648-12-5(Hazardous Substances Data)

Usage

General Description

2-CHLORO-3-TRICHLOROMETHYLPYRIDINE is a chemical compound that belongs to the class of pyridine derivatives. It is characterized by the presence of a chloro group on the second carbon atom and three trichloromethyl groups attached to the third carbon atom of the pyridine ring. This chemical is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also known for its potent antimicrobial properties, making it a valuable ingredient in the development of pesticides and disinfectants. Additionally, 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE has been studied for its potential use as a building block in organic synthesis and is a valuable compound in the field of chemical research and development.

InChI:InChI=1/C6H3Cl4N/c7-5-4(6(8,9)10)2-1-3-11-5/h1-3H

Upstream product

• 108-99-6 3-Methylpyridine 
• 609-71-2 2-hydroxy-3-carboxypyridine 

Downstream Products

• 2942-59-8 2-chloronicotinic acid 
• 58819-72-0 2,6-dimethoxypyridine-3-carboxaldehyde 
• 95652-80-5 2-chloro-6-methoxy-3-pyridine-carboxaldehyde 
• 121643-43-4 2-chloro-3-dichloromethyl-6-methoxypyridine 
• 95652-79-2 2-chloro-3-(dimethoxymethyl)-6-methoxypyridine 

Relevant articles and documents

Refining and purification method and drying treatment apparatus for 2-chloronicotinic acid

The invention discloses a refining and purification method and a drying treatment apparatus for 2-chloronicotinic acid. The method comprises the following steps: reacting 3-methylpyridine with chlorine to produce 2-chloro-3-trichloromethylpyridine; hydrolyzing 2-chloro-3-trichloromethylpyridine to obtain a 2-chloronicotinic acid reaction product; and purifying and drying the 2-chloronicotinic acidreaction product by using the apparatus. The apparatus is applicable to drying treatment of 2-chloronicotinic acid and has a simple structure. The refining and purification method for 2-chloronicotinic acid can greatly improve the quality and purity of a 2-chloronicotinic acid product.

Synthesis method of 2-chloro-trichloromethyl pyridine

The invention discloses a synthesis method of 2-chloro-trichloromethyl pyridine. The synthesis method comprises following steps: (1) oxidation reactions: dropwise adding an oxidizing agent into 3-trichloromethyl pyridine, and carrying out oxidation reactions at a temperature of 70 to 80 DEG C in the presence of a catalyst to obtain 3-chloromethyl pyridine oxynitride; and (2) chlorination reactions: carrying out chlorination reactions between 3-chloromethyl pyridine oxynitride obtained in the step (1) and a chlorination agent at a temperature of 20 to 25 DEG C to obtain the target product 2-chloro-trichloromethyl pyridine; wherein the solvent is an organic solvent and an organic alkali is taken as an acid-binding agent in chlorination reactions. The synthesis method is simple, the reactionconditions are mild, the yield is high, and the product purity can reach 95% or more.

Vapor phase catalytic chlorination of ?-picoline

2-Chloro-5-trichloromethylpyridine is obtained by chlorinating β-picoline in the vapor phase using a Mordenite zeolite or a supported palladium catalyst.