588729-97-9

Basic information

• Product Name: Benzamide, N-(6-bromothiazolo[4,5-b]pyridin-2-yl)-
• CAS NO: 588729-97-9
• Molecular Formula: C13H8BrN3OS
• Molecular Weight: 334.196
• Mol File: 588729-97-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(6-bromothiazolo[4,5-b]pyridin-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(6-bromothiazolo[4,5-b]pyridin-2-yl)-(588729-97-9)
• EPA Substance Registry System: Benzamide, N-(6-bromothiazolo[4,5-b]pyridin-2-yl)-(588729-97-9)

Safety Data

• Hazardous Substances Data: 588729-97-9(Hazardous Substances Data)

Upstream product

• 381233-96-1 2-amino-3-iodo-5-bromopyridine 
• 532-55-8 Benzoyl isothiocyanate 
• 38185-55-6 5-bromo-3-chloropyridin-2-ylamine 
• 98-88-4 benzoyl chloride 
• 588729-96-8 N-benzoyl-N'-(5-bromo-3-chloro-2-pyridyl)thiourea 

Downstream Products

• 588730-01-2 N-(6-bromo-thiazolo[5,4-b]pyridine-2-yl)-benzamide 
• 588729-98-0 N-(6-phenyl-thiazolo[4,5-b]pyridin-2-yl)-benzamide 
• 857970-06-0 2-amino-6-bromo[1,3]thiazolo[4,5-b]pyridine 
• 960535-44-8 6-bromo-2-chlorothiazolo[4,5-b]pyridine 
• 588730-02-3 N-(6-phenyl-thiazol[5,4-b]pyridin-2-yl)-benzamide 

Relevant articles and documents

1, 3, 4, 5-TETRAHYDRO-2H-PYRIDO[4,3-B]INDOLE DERIVATIVES FOR THE TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH TAU AGGREGATES LIKE ALZHEIMER'S DISEASE

The present invention relates to novel compounds that can be employed in the treatment, alleviation or prevention of a group of disorders and abnormalities associated with Tau (Tubulin associated unit) protein aggregates including, but not limited to, Neurofibrillary Tangles (NFTs), such as Alzheimer's disease (AD).

NOVEL BICYCLIC HETEROCYCLIC COMPOUND

Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.

Oxidative cyclization of N-methyl- and N-benzoylpyridylthioureas. Preparation of new thiazolo[4,5-b] and [5,4-b]pyridine derivatives

Cyclization of N-methyl- and N-benzoylpyridylthioureas, prepared from the corresponding aminopyridines, has been realized using various conditions. With bromine in acetic acid or potassium ferricyanide, the cyclization occurred on the nitrogen of the pyridine ring and pyridinium salts or 1,2,4-thiadiazolo[2,3-a]pyridylidene systems were obtained. On the other hand, treatment of the thioureas with sodium methoxide in N-methylpyrrolidinone (NMP) led to formation of thiazolo[4,5-b] and [5,4-b]pyridines, which are interesting targets for biological evaluation.