5922-25-8Relevant articles and documents
Synthesis method of 2-(4-aminophenyl)-5-aminobenzimidazole
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Paragraph 0239-0242; 0244-0245, (2022/01/20)
The present invention provides a synthesis method of 2- (4-aminophenyl)-5-aminobenzimidazole, comprising the following steps: step 1, preparation of N,N'-bis (4-nitro - α- chlorinated) phenylmethylene p-phenylenediamine; step 2, using N, N'-bis(4-nitro - α- chloro) phenylmethylene p-phenylenediamine preparation N, N'-bis (4-nitro - α - imino) benzyl p-phenylenediamine; step 3, using N, N'-di (4-nitro - α - imino) benzyl p-phenylenediamine preparation 2- ( Step 4, 2-(4-nitro)phenyl-5-aminobenzimidazole was hydrogenated with a hydrogenation catalyst and hydrogen to give 2-(4-amino)phenyl-4-aminobenzimidazole. The present invention is intended to achieve a low production cost and high safety, less harmful pollutants 2- (4-aminophenyl) -5-aminobenzimidazole synthesis method.
Synthesis of distamycin and netropsin analogs: Part II - DNA binding bisquaternary ammonium heterocycles analogous to NSC 101327
Rao,Sasisekharan
, p. 503 - 507 (2007/10/02)
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