59338-85-1

Basic information

• Product Name: methyl 4,5-diamino-o-anisate
• Synonyms: methyl 4,5-diamino-o-anisate;2-Methoxy 4,5-Diaminobenzoic acid;BENZOIC ACID, 4,5-DIAMINO-2-METHOXY;4,5-Diamino-2-methoxybenzoic acid methyl ester;Einecs 261-704-3
• CAS NO: 59338-85-1
• Molecular Formula: C9H12N2O3
• Molecular Weight: 196.20318
• EINECS: 261-704-3
• Mol File: 59338-85-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 420°C at 760 mmHg
• Flash Point: 242.1°C
• Appearance: /
• Density: 1.258g/cm³
• Vapor Pressure: 2.92E-07mmHg at 25°C
• Refractive Index: 1.597
• PKA: 3.62±0.10(Predicted)
• CAS DataBase Reference: methyl 4,5-diamino-o-anisate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4,5-diamino-o-anisate(59338-85-1)
• EPA Substance Registry System: methyl 4,5-diamino-o-anisate(59338-85-1)

Safety Data

• Hazardous Substances Data: 59338-85-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H12N2O3/c1-13-8-4-7(11)6(10)3-5(8)9(12)14-2/h3-4H,10-11H2,1-2H3

Upstream product

• 27492-84-8 Methyl 4-amino-2-methoxybenzoate 
• 4093-41-8 methyl 4-acetamido-2-methoxy-5-nitrobenzoate 
• 4093-29-2 methyl 4-(acetylamino)-o-anisate 
• 59338-84-0 methyl 4-amino-2-methoxy-5-nitrobenzoate 
• 99459-57-1 2-methoxy-4,5-dinitro-benzoic acid methyl ester 
• 186581-53-3 diazomethane 
• 90833-87-7 4,5-di(amino)-2-hydroxybenzoic acid 

Downstream Products

• 59338-86-2 6-methoxy-1H-benzotriazole-5-carboxylic acid methyl ester 

Relevant articles and documents

ARYL AND HETEROARYL-CARBOXAMIDE SUBSTITUTED HETEROARYL COMPOUNDS AS TYK2 INHIBITORS

Novel carboxamide substituted compounds of Formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Tyrosine Kinase 2 (Tyk2).

ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I" PATHWAY AND METHODS OF USE THEREOF

The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.

As neuroprotective agents of pharmaceutical compounds

The invention discloses a medicinal compound as a neuroprotective agent. The medicinal compound is a neuronal nitric oxide synthase-postsynaptic density protein 95 (nNOS-PSD95) decoupling agent. The medicinal compound is a benzene ring derivative shown in the general formula (I) or its pharmaceutically acceptable salt. The invention further discloses a preparation method of the medicinal compound and a use of the medicinal compound in prevention and treatment on neuronal damage influence-caused diseases.