59387-82-5Relevant articles and documents
Novel and efficient synthesis of substituted quinoline-1-oxides and the complex compounds SnL2Cl2 (L=2-aminoquinoline-1-oxides) with the aid of stannous chloride
Fu, Lei,Lin, Wei,Xu, Pan,Xi, Yu-Kun,Wang, Man-Man,Shi, Da-Qing
experimental part, p. 7782 - 7786 (2012/09/22)
A novel and efficient approach to the synthesis of substituted quinoline-1-oxides and the complex compounds SnL2Cl2 (L=2-aminoquinoline-1-oxides) was developed. The reaction has fancy selectivity when 3-(2-nitrophenyl)acrylonitriles were treated with the aid of SnCl 2 reagent under the same conditions. When R is -CN or -COOR′ the complex compounds SnL2Cl2 (L=2-aminoquinoline-1- oxides) were obtained. Whereas, when R is H or aryl another series of substituted quinoline-1-oxides were formed. The products have been screened for their anticancer activities.