596-59-8

Basic information

• Product Name: Morphinan-6-one,7,8-didehydro-4-hydroxy-3-methoxy-17-methyl-, (14a)- (9CI)
• Synonyms: 14a-Morphinan-6-one,7,8-didehydro-4-hydroxy-3-methoxy-17-methyl- (8CI); b-Thebainone (7CI); b-Thebainon A; b-Thebainone A
• CAS NO: 596-59-8
• Molecular Formula: C18H21 N O3
• Molecular Weight: 299.37
• Mol File: 596-59-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Morphinan-6-one,7,8-didehydro-4-hydroxy-3-methoxy-17-methyl-, (14a)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Morphinan-6-one,7,8-didehydro-4-hydroxy-3-methoxy-17-methyl-, (14a)- (9CI)(596-59-8)
• EPA Substance Registry System: Morphinan-6-one,7,8-didehydro-4-hydroxy-3-methoxy-17-methyl-, (14a)- (9CI)(596-59-8)

Safety Data

• Hazardous Substances Data: 596-59-8(Hazardous Substances Data)

Upstream product

• 916225-97-3 2-iodo-6-methoxy-3-(2,2-dimethoxyethyl)phenol 
• 467-13-0 dihydrocodeinone 
• 141849-31-2 trans-morphinan 
• 123965-08-2 ent-4-hydroxy-3-methoxy-17-methyl-morphin-7-en-6-one-(2,4-dinitro-phenylhydrazone) 

Downstream Products

• 467-98-1 (±)-thebainone A 
• 847-86-9 (-)-Dihydrothebainon 

Relevant articles and documents

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Improved synthesis of dihydrothebainone and its 14 β-epimer

An improved synthesis for the preparation of diastereomerically pure dihydrothebainone (1) from thebaine (3) is reported. A 41% overall yield was realized over three steps via direct transformation of dihydrothebaine-Φ (4) to thebainone-A (6) with 6N HCl.

Synthesis of 7,8-didehydro-3,4-dimethoxy-17-methylmorphinan-6-one and the regioselective reduction of the keto function

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