59664-75-4

Basic information

• Product Name: Phosphonic acid, [chloro(phenylthio)methyl]-, diethyl ester
• CAS NO: 59664-75-4
• Molecular Formula: C11H16ClO3PS
• Molecular Weight: 294.739
• Mol File: 59664-75-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [chloro(phenylthio)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [chloro(phenylthio)methyl]-, diethyl ester(59664-75-4)
• EPA Substance Registry System: Phosphonic acid, [chloro(phenylthio)methyl]-, diethyl ester(59664-75-4)

Safety Data

• Hazardous Substances Data: 59664-75-4(Hazardous Substances Data)

Upstream product

• 25411-73-8 diethyl diazomethylphosphonate 
• 882-33-7 diphenyldisulfane 
• 3084-40-0 diethyl (1-hydroxymethyl)phosphonate 
• 7205-91-6 phenylthiomethyl chloride 
• 38066-16-9 diethyl [(phenylthio)methyl]phosphonate 
• 50746-65-1 Diethyl (phenylsulfinyl)methylphosphonate 

Downstream Products

• 79092-59-4 (Methoxy-phenylsulfanyl-methyl)-phosphonic acid diethyl ester 
• 123277-91-8 phenylthio(n-propylthio)methanephosphonate 
• 59590-51-1 (Ethoxy-phenylsulfanyl-methyl)-phosphonic acid diethyl ester 
• 123277-93-0 isobutylthio(phenylthio)methanephosphonate 
• 103725-11-7 α-chloro-α-diethoxyphosphorylmethyl phenyl sulfone 
• 59664-74-3 (Chloro-cyclohexylidene-methylsulfanyl)-benzene 
• 83818-66-0 C₁₄H₁₁ClS 
• 73778-53-7 S,S-diphenylacetal of diethyl oxomethanephosphonate 
• 123277-92-9 isopropylthio(phenylthio)methanephosphonate 
• 103725-14-0 1-((Z)-2-Benzenesulfonyl-2-chloro-vinyl)-3-nitro-benzene 
• 103725-13-9 1-((Z)-2-Benzenesulfonyl-2-chloro-vinyl)-4-nitro-benzene 
• 103725-15-1 [4-((Z)-2-Benzenesulfonyl-2-chloro-vinyl)-phenyl]-dimethyl-amine 
• 103725-16-2 1-((Z)-2-Benzenesulfonyl-2-chloro-vinyl)-4-chloro-benzene 
• 103725-17-3 C₁₆H₁₃ClO₂S 

Relevant articles and documents

Wittig–Horner mediated synthesis of 4-vinyl sulfide derivatives of pyrazoles

The synthesis of a series of 4-vinyl sulfide derivatives of 1,3-diarylpyrazoles, including their corresponding sulfoxides and sulfones, is reported. Access to the target vinyl sulfides was stereoselectively achieved, in moderate to good yields, by the n-BuLi-mediated Wittig–Horner reaction of 4-formylpyrazoles with arylthiophosphonates and α-chloroarylthiophosphonates in dimethoxyethane. Their oxidation with H2O2in AcOH and mCPBA in CH2Cl2afforded satisfactory yields of the expected vinyl sulfoxides and vinyl sulfones, respectively. Enrichment in the more stable isomers during both oxidation processes was detected and a plausible general mechanistic explanation was given to these observations.

Free radical desulfenylation and deselenylation of α-sulfur and α-seleno substituted phosphonates with the n-Bu3SnH/AIBN reagents system.

Selestive desulfenylation and deselenylation of α-sulfur- and α-seleno-substituted phosphonates under free radical condition are described.Chemoselectivity and scope of title reaction were studied using phosphonates additionaly functionalized in the α-position alkyl, phenyl,ethoxy,chloro,carbonyl and sulfenyl groups.It was found the reduction of a halogen tolerates the presence of the sulfenyl group and the latter could be reduced in the presence of the sulfinyl and sulfonyl moieties.Moreover,one sulfenyl group was selectively removed from α-phosphoryl dithioacetals and the phenylsulphenyl group was reduced preferentially in the presence of the methylsulfenyl one. Key words:Desulfenylation,deselenylation,α-phosphoryl sulfides,α-phosphoryl selenides, tri-n-butyltinhydride,α,α-azaisobutyronitrile.

Synthesis of Chlorovinyl Phenyl Sulfides and Sulfones from Diethyl Chloro-(phenylthio)-methanephosphonate

-