5982-23-0

Basic information

• Product Name: 3-(2-Carboxybenzyl)isocoumarin
• Synonyms: 3-(2-Carboxybenzyl)isocoumarin;F-1375
• CAS NO: 5982-23-0
• Molecular Formula: C₁₇H₁₂O₄
• Molecular Weight: 280.2748
• Mol File: 5982-23-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 208-209 °C
• Boiling Point: 493.6°Cat760mmHg
• Flash Point: 186.9°C
• Appearance: /
• Density: 1.361g/cm³
• Vapor Pressure: 1.47E-10mmHg at 25°C
• Refractive Index: 1.658
• PKA: 4.05±0.36(Predicted)
• CAS DataBase Reference: 3-(2-Carboxybenzyl)isocoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Carboxybenzyl)isocoumarin(5982-23-0)
• EPA Substance Registry System: 3-(2-Carboxybenzyl)isocoumarin(5982-23-0)

Safety Data

• Hazardous Substances Data: 5982-23-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H12O4/c18-16(19)14-7-3-1-5-11(14)9-13-10-12-6-2-4-8-15(12)17(20)21-13/h1-8,10H,9H2,(H,18,19)

Upstream product

• 85-44-9 phthalic anhydride 
• 89-51-0 Homophthalic acid 
• 703-59-3 homophthalic anhydride 
• 3958-57-4 1-bromomethyl-3-nitrobenzene 
• 22115-41-9 2-(bromomethyl)benzonitrile 

Downstream Products

• 115373-07-4 2-(2,5-Dihydro-2-methyl-1-oxo-1H-2,3-benzodiazepin-4-ylmethyl)-benzoesaeure 
• 14736-39-1 2-(1-oxo-isochroman-3-ylmethyl)-benzoic acid methyl ester 
• 16281-55-3 1,3-Bis-(2-hydroxymethyl-phenyl)-propanol-⁽²⁾ 
• 14736-35-7 1,3-Bis-(2-methoxycarbonyl-phenyl)-aceton 
• 115373-08-5 2-(2-Amino-1,2-dihydro-1-oxo-isochinolin-3-ylmethyl)-benzoesaeure 
• 115392-74-0 2-(2,5-Dihydro-1-oxo-1H-2,3-benzodiazepin-4-ylmethyl)-benzoesaeure 
• 115373-03-0 2-(1,2-Dihydro-2-hydroxy-1-oxo-isochinolin-3-ylmethyl)-benzoesaeure 
• 115373-00-7 2-(1,2-Dihydro-1-oxo-isochinolin-3-ylmethyl)-benzoesaeure 

Relevant articles and documents

A speedy route to sterically encumbered, benzene-fused derivatives of privileged, naturally occurring hexahydropyrrolo[1,2-b]isoquinoline

A series of 15 benzene-fused hexahydropyrrolo[1,2-b]isoquinolonic acids with substantial degree of steric encumbrance has been prepared via a novel variant of the Castagnoli-Cushman reaction of homophthalic anhydride (HPA) and various indolenines. The employment of a special kind of a cyclic imine component reaction allowed, for the first time, isolating a Mannich-type adduct between HPA and an imine component which has been postulated but never obtained in similar reactions.

New highly diastereoselective Perkin/Michael addition domino reaction between homophthalic anhydride and aromatic aldehydes: A facile approach to blue-fluorescent dibenzo[c,h]chromenones

A series of new trans-11-aryl-6-oxo-6H-dibenzo[c,h]chromene-12-carboxylic acids has been synthesised through anew Perkin/Michael addition domino reaction between homophthalic anhydride and aromatic aldehydes. The synthesis is straightforward and gives goo

Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c] isoquinolin-5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one

(Chemical Equation Presented) The synthesis of 6,11-dihydro-5H-indeno[1,2- c]isoquinolin-5-ones from the base-promoted condensation reaction of homophthalic anhydride and 2-(bromomethyl)-benzonitrile and a convenient method for the synthesis of indolo[3,2-c]isoquinolinones are described.