60046-25-5 Usage
Description
D-GLUCOHEPTONO-1,4-LACTONE is a naturally occurring compound that serves as a key intermediate in the synthesis of various bioactive molecules. It is derived from the root and stem bark of Goniothamus howii (Annonaceae) and has been identified as an active antitumor constituent. This lactone is characterized by its unique chemical structure, which allows it to be a versatile building block in the development of new pharmaceutical agents.
Uses
Used in Pharmaceutical Industry:
D-GLUCOHEPTONO-1,4-LACTONE is used as a key intermediate in the synthesis of Howiinol A and its analogs for their antitumor properties. Howiinol A, an active antitumor constituent from the root and stem bark of Goniothamus howii (Annonaceae), can be synthesized in 9 steps from α-D-glucoheptonic γ-lactone. The synthesis of Howiinol A and its analogs aims to discover new antitumor compounds with high potency, offering potential therapeutic benefits in cancer treatment.
Additionally, D-GLUCOHEPTONO-1,4-LACTONE has been utilized in the synthesis of twenty-six analogs, further expanding the scope of its applications in the search for novel antitumor compounds. This highlights the importance of D-GLUCOHEPTONO-1,4-LACTONE as a valuable precursor in the development of innovative pharmaceutical agents targeting cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 60046-25-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,0,4 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60046-25:
(7*6)+(6*0)+(5*0)+(4*4)+(3*6)+(2*2)+(1*5)=85
85 % 10 = 5
So 60046-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H12O7/c8-1-2(9)3(10)6-4(11)5(12)7(13)14-6/h2-6,8-12H,1H2/t2-,3-,4+,5-,6+/m1/s1
