6047-29-6

Basic information

• Product Name: 5,6,11,12-TETRAHYDRODIBENZ[B,F]AZOCIN-6-ONE
• Synonyms: DIBENZAZOCINONE;5,6,11,12-TETRAHYDRODIBENZ[B,F]AZOCIN-6-ONE;11,12-Dihydrodibenz[b,f]azocin-6(5H)-one;5,6,11,12-Tetrahydrodibenzo[b,f]azocine-6-one;5,6,11,12-Tetrahydrodibenz[b,f]azocin-6-oneDibenzazocinone;11,12-Dihydrodibenzo[b,f]azocin-6(5H)-one
• CAS NO: 6047-29-6
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.27
• EINECS: 227-942-7
• Mol File: 6047-29-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 246-248 °C(lit.)
• Boiling Point: 364.56°C (rough estimate)
• Flash Point: 174.668°C
• Appearance: /
• Density: 1.0707 (rough estimate)
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• PKA: 13.48±0.20(Predicted)
• CAS DataBase Reference: 5,6,11,12-TETRAHYDRODIBENZ[B,F]AZOCIN-6-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,11,12-TETRAHYDRODIBENZ[B,F]AZOCIN-6-ONE(6047-29-6)
• EPA Substance Registry System: 5,6,11,12-TETRAHYDRODIBENZ[B,F]AZOCIN-6-ONE(6047-29-6)

Safety Data

• Hazard Codes: N
• Statements: 51/53
• Safety Statements: 24/25-61
• WGK Germany: 3
• Hazardous Substances Data: 6047-29-6(Hazardous Substances Data)

Usage

General Description

5,6,11,12-Tetrahydrodibenz[b,f]azocin-6-one is a chemical compound that belongs to the class of dibenzazocine alkaloids. It is a tricyclic compound containing a dibenzazocine ring system with a ketone functional group at the 6th position. 5,6,11,12-TETRAHYDRODIBENZ[B,F]AZOCIN-6-ONE has been identified in various natural sources and has shown potential pharmacological activities, including anti-inflammatory and analgesic properties. Its structure and properties make it a potential candidate for the development of new therapeutic agents in the pharmaceutical industry. The compound's unique structure and potential biological activities make it an interesting target for further research and exploration.

InChI:InChI=1/C15H13NO/c17-15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)16-15/h1-8H,9-10H2,(H,16,17)

Upstream product

• 1021-91-6 N-[tricyclo[9.4.0.0^3,8]pentadeca-1⁽¹¹⁾,3,5,7,9,12,14-heptaen-2-ylidene]hydroxylamine 
• 2222-33-5 dibenzosuberenon 
• 833-48-7 dibenzosuberane 
• 1785-74-6 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one oxime 
• 1210-35-1 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one 

Downstream Products

• 23194-93-6 2-azatricyclo[10.4.0.0^4,9]hexadeca-1⁽¹⁶⁾,4⁽⁹⁾,5,7,10,12,14-heptene 
• 1384870-47-6 1-{[6-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-6-oxohexanoyl]oxy}pyrrolidine-2,5-dione 
• 136620-67-2 2-[2-(2-aminophenyl)ethyl]benzoic acid hydrochloride 

Relevant articles and documents

Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis

Strain-promoted azide–alkyne cycloaddition using dibenzoazacyclooctyne (DBCO) is widely applied in copper-free bioorthogonal reactions. Reported here is the efficient acid-promoted rearrangement and silver-catalyzed amidation of DBCO, which alters its click reactivity robustly. In the switched click reaction, DBCO, as a caged acylation reagent, enables rapid peptide/protein modification after decaging facilitated by silver catalysts, rendering site-specific conjugation of an IgG antibody by a Fc-targeting peptide.

Iron-catalyzed C-H and C-C bond cleavage: A direct approach to amides from simple hydrocarbons

Something functional: The title reaction proceeds in the presence of azide and water to deliver amides in high yields, and it can be used in a ring-expansion strategy to generate lactams. A mechanism is proposed based on experimental results. This reaction offers a new approach to functionalizing simple and readily available hydrocarbons. DDQ=2,3-dichloro-5,6-dicyano-1,4- benzoquinone. Copyright

THE SYNTHESIS OF SOME N-SUBSTITUTED DIBENZ(B,F)AZOCINE DERIVATIVES.

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