6049-46-3

Basic information

• Product Name: 2-Benzyl-4-oxopentanoic acid
• CAS NO: 6049-46-3
• Molecular Weight: 206.241
• Mol File: 6049-46-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Benzyl-4-oxopentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzyl-4-oxopentanoic acid(6049-46-3)
• EPA Substance Registry System: 2-Benzyl-4-oxopentanoic acid(6049-46-3)

Safety Data

• Hazardous Substances Data: 6049-46-3(Hazardous Substances Data)

Upstream product

• 688361-39-9 5-acetonyl-5-benzyl-barbituric acid 
• 97677-88-8 2-Benzyl-2-(2-oxo-propyl)-malonic acid diethyl ester 

Downstream Products

• 36092-42-9 2-benzylsuccinic acid 
• 14557-92-7 2-(2-phenylmethyl)-4-methyl-4-butanolide 
• 51849-73-1 3-benzyl-5,5-dimethyltetrahydrofuran-2-one 
• 97677-85-5 2-Benzyl-4-methyl-pentane-1,4-diol 
• 97677-86-6 4-Benzyl-2-methyl-tetrahydro-furan 
• 97677-87-7 4-benzyl-2,2-dimethyltetrahydrofuran 
• 97677-84-4 α-Benzyl-γ-hydroxy-valerol 
• 97677-89-9 2-Benzyl-4-hydroxy-4-methyl-pentanoic acid 

Relevant articles and documents

The Stereoselective Synthesis of 2-Alkyl γ-Keto Acid and Heterocyclic Ketomethylene Peptide Isostere Core Units Using Chiral Alkylation by 2-Triflyloxy Esters

A simple and general protocol for the enentioselective preparation of γ-keto acids and heterocyclic γ-keto acids which have an alkyl group at C-2 is reported.The alkyl group is introduced by chiral alkylation using a scalemic 2-triflyoxy ester.The alkylation takes place with inversion of configuration and is compatible with a variety of alkyl groups.This methodology is thus wellsuited for the preparation of a wide variety of ketomethylene peptide isosteres.