60516-11-2Relevant articles and documents
Synthesis of Potential Metabolites of 4-Methyl-1-piperazine
Anjaneyulu B.
, p. 657 - 661 (2007/10/02)
4-Methyl-1-piperazine (1) is an experimental antifilarial drug.In order to investigate its metabolic fate in laboratory animals and also man several potential metabolites, arising from general metabolic conversions of 1, viz.N-oxidation (8), N-demethylation and acetylation (11) and (12), desulphuration (15), nitro group reduction to aryl amino (16) and further acetylation to arylacetamido (17), have been synthesized for identification/quantitation purposes.