6149-34-4

Basic information

• Product Name: 1,4-Benzenediamine,N1-(4-nitrophenyl)-
• Synonyms: 1,4-Benzenediamine,N-(4-nitrophenyl)- (9CI); p-Phenylenediamine, N-(p-nitrophenyl)- (6CI,7CI,8CI);4-Amino-4'-nitrobenzanilide; 4-Amino-4'-nitrodiphenylamine;4-Nitro-4'-aminodiphenylamine; NSC 159352
• CAS NO: 6149-34-4
• Molecular Formula: C₁₂H₁₁N₃O₂
• Molecular Weight: 229.2346
• Mol File: 6149-34-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 437.7°C at 760 mmHg
• Flash Point: 218.5°C
• Appearance: /
• Density: 1.351g/cm³
• Vapor Pressure: 7.32E-08mmHg at 25°C
• Refractive Index: 1.711
• CAS DataBase Reference: 1,4-Benzenediamine,N1-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenediamine,N1-(4-nitrophenyl)-(6149-34-4)
• EPA Substance Registry System: 1,4-Benzenediamine,N1-(4-nitrophenyl)-(6149-34-4)

Safety Data

• Hazardous Substances Data: 6149-34-4(Hazardous Substances Data)

Usage

General Description

1,4-Benzenediamine,N1-(4-nitrophenyl)- is a chemical compound with the molecular formula C12H10N4O2. It is also known as 4-Nitro-1,2-phenylenediamine and is commonly used in the manufacture of various products such as dyes, pigments, and photographic chemicals. 1,4-Benzenediamine,N1-(4-nitrophenyl)- is a yellow crystalline solid that is soluble in water and has a melting point of 187-192°C. It is a known skin and eye irritant and may cause allergic skin reactions, so proper protective measures should be taken when handling this chemical.

InChI:InChI=1/C12H11N3O2/c13-9-1-3-10(4-2-9)14-11-5-7-12(8-6-11)15(16)17/h1-8,14H,13H2

Upstream product

• 7664-93-9 sulfuric acid 
• 91-29-2 4-amino-4'-nitrodiphenylamine-2'-sulfonic acid 
• 100-00-5 4-chlorobenzonitrile 
• 106-50-3 1,4-phenylenediamine 
• 350-46-9 4-Fluoronitrobenzene 
• 586-78-7 para-nitrophenyl bromide 

Downstream Products

• 36071-20-2 4-(4-nitro-anilino)-benzenediazonium-betaine 
• 60516-11-2 4-Acetamido-4'-nitrodiphenylamine 
• 2420-88-4 4,4′-diaminodiphenylmethylamine 
• 537-65-5 4,4'-diaminodiphenylamine 
• 108272-17-9 N-acetyl-4,4'-diaminodiphenylamine 

Relevant articles and documents

DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN

The is provided a compound of formula I or II or physiologically acceptable salts or solvates, or oxidised derivatives thereof: where R1 to R3, R13 and R14 are as defined herein. Also disclosed herein are methods of dyeing hair or (temporarily) tattooing the skin using the compounds of formula I or II (or physiologically acceptable salts or solvates, or oxidised derivatives thereof) in a suitable composition.

Synthesis method of 4,4'-diamino diphenylamine

The invention discloses a synthesis method of 4,4'-diamino diphenylamine. The synthesis method comprises the following operation steps that phenylenediamine and nitrophenylcarbimide are used as reactants; under certain reaction conditions, one amidogen on a benzene ring substitutes chlorine on the nitrophenylcarbimide under the effect of alkali to obtain a preliminary product of 4-nitro-4'-aminodiphenylamine; then, nitryl of 4-nitro-4'-aminodiphenylamine is subjected to hydrogenation reduction under the effect of catalysts to obtain a final product of 4,4'-diamino diphenylamine. When the scheme is adopted, the purchasing and the transportation of raw materials are very convenient; the product yield is high; the cost is low; the operation is simple; the environment pollution is little, so that the synthesis method has good industrial development prospects.

Design, synthesis and antitumor activity of novel cis-furoquinoline derivatives

A series of novel cis-furoquinoline derivatives was synthesized and tested for their antitumor activities in vitro against HepG2 cells, Lu-04 cells and Leu02 cells to evaluate structure-activity relationships. Assay-based antiproliferative activity study revealed that several compounds had significant effects on cytotoxicity, among which compounds 2f, 2l, 2q were found to be the most active compounds. Above all, compounds 2f, 2l, 2q would be potential anticancer agents which deserved further research.