606-17-7 Usage
Chemical Properties
Crystalline Solid
Originator
Cholografin,Squibb,US,1954
Uses
Different sources of media describe the Uses of 606-17-7 differently. You can refer to the following data:
1. Diagnostic aid (radiopaque medium-cholecystographic).
2. antihypertensive, diuretic, activates K channels and AMPA receptors
Manufacturing Process
125 g of 2,4,6-triiodo-3-amino benzoic acid are dissolved in 250 cc of
chlorobenzene and 15 g of adipic acid dichloride are added at a temperature
between 110° and 130°C drop by drop to the solution. After evolution of
hydrochloric acid (about 2 to 3 hours) has ceased, the precipitated crude
adipic acid di-(3-carboxy-2,4,6-triiodo anilide) of the above formula is filtered
hot with suction, washed with chlorobenzene, extracted by boiling with
methanol and, for purification, dissolved in an amount of methanolic caustic
soda solution required for neutralization, filtered with charcoal, and
precipitated with dilute hydrochloric acid. Yield: 82.3 g, MP 306° to 308°C
(with decomposition).
Brand name
Pharmaceutic necessity for Iodipamide
Meglumine [Injection]. Cholografin (Bristol-Myers
Squibb).
Therapeutic Function
Diagnostic aid (radiopaque medium)
Hazard
Toxic by ingestion.
Check Digit Verification of cas no
The CAS Registry Mumber 606-17-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,0 and 6 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 606-17:
(5*6)+(4*0)+(3*6)+(2*1)+(1*7)=57
57 % 10 = 7
So 606-17-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34)
606-17-7Relevant articles and documents
Liebster et al.
, p. 1474 (1959)
Iodinated aromatic propanedioates
-
, (2008/06/13)
Compounds having the structure STR1 where (Z--COO is the residue of an iodinated aromatic acid; R1 and R2 are independently alkyl, fluoroalkyl, cycloalkyl, aryl or aralkyl; and R3 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, cyano, sulfonate, carboxamido, sulfonamido, CO2 -alkyl, CO2 -aryl or CO2 -aralkyl; are useful as contrast agents in x-ray imaging compositions and methods.
