60634-74-4Relevant articles and documents
Design and synthesis of an Fmoc-SPPS-compatible amino acid building block mimicking the transition state of phosphohistidine phosphatase
Eerland, Martijn F.,Hedberg, Christian
experimental part, p. 2047 - 2052 (2012/04/23)
The synthesis of a sulfonamide-based transition-state (TS) analogue of enzymatic phosphohistidine dephosphorylation as an amino acid building block is presented, together with the proof-of-concept of its incorporation into peptides. Key features include f
SULFONATION OF SUBSTITUTED AZOLES WITH SULFUR TRIOXIDE IN DICHLOROETHANE
Bochkareva, T. P.,Passet, B. V.,Popov, K. R.,Platonova, N. V.,Koval'chuk, T. I.
, p. 1084 - 1089 (2007/10/02)
A novel method has been developed for the synthesis of sulfonic acids of five-membered heterocycles containing two heteroatoms, with a solution of sulfur trioxide in 1,2-dichloroethane.High yields of the required products are obtained, under conditions which are mild in comparison with those used in earlier methods.The mechanism of sulfonation is discussed, and some azole.SO3 complexes have been obtained and described.