60857-45-6

Basic information

• Product Name: (2-methoxyphenyl)(3-phenyloxiran-2-yl)methanone
• Synonyms: (2-methoxyphenyl)(3-phenyloxiran-2-yl)methanone
• CAS NO: 60857-45-6
• Molecular Weight: 254.285
• Mol File: 60857-45-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (2-methoxyphenyl)(3-phenyloxiran-2-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methoxyphenyl)(3-phenyloxiran-2-yl)methanone(60857-45-6)
• EPA Substance Registry System: (2-methoxyphenyl)(3-phenyloxiran-2-yl)methanone(60857-45-6)

Safety Data

• Hazardous Substances Data: 60857-45-6(Hazardous Substances Data)

Upstream product

• 579-74-8 2-Methoxyacetophenone 
• 100-52-7 benzaldehyde 
• 6948-61-4 (E)-1-(2-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 100-42-5 styrene 
• 135-02-4 ortho-anisaldehyde 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 40524-62-7 1-(2-methoxyphenyl)-3-phenyl-2-propene-1-one 

Downstream Products

• 912345-64-3 3-hydroxy-1-(2-methoxyphenyl)-3-phenylpropan-1-one 
• 5543-03-3 1-(2-methoxy-phenyl)-3-phenyl-propane-1,2-dione 
• 95279-91-7 α,2'-dimethoxy-chalcone 
• 4982-10-9 3-Chlor-1-(2-methoxy-phenyl)-3-phenyl-propan-2-ol-1-on 
• 854632-85-2 3-(2-methoxy-phenyl)-3-oxo-2-phenyl-propionaldehyde 
• 4982-14-3 α-hydroxy-2'-methoxy-chalcone 
• 93435-11-1 2-hydroxy-2-(2-methoxy-phenyl)-3-phenyl-propionic acid 
• 5533-64-2 5-benzyl-5-(2-methoxy-phenyl)-imidazolidine-2,4-dione 

Relevant articles and documents

A high-yielding protocol for the synthesis of 4,5-diarylpyrimidin-2-amine derivatives from chalcones

A novel, high yielding and versatile protocol was achieved for the synthesis of 4,5-diaryl-2-pyrimidinamine derivatives from chalcones. The synthesis was accomplished by converting the chalcones into 3-chloro-2,3-diaryl-2-propen-1-ones followed by subsequent reaction with amidine derivatives.

Asymmetric epoxidation of α,β-unsaturated ketones via an amine-thiourea dual activation catalysis

A simple asymmetric epoxidation method is developed to effectively synthesize chiral α-carbonyl epoxides through an amine-thiourea dual activation catalysis. In this method, TBHP, as an oxidant, determined the reaction rate, and the chiral amine-thiourea catalyst effectively controlled the stereoselectivity of the reaction, and KOH promoted deprotonation. 22 examples of α,β-unsaturated ketones with various substituent groups are smoothly converted into α-carbonyl epoxides with moderate to excellent enantiomeric excess.

Preparation of mesoporous zeolite ETS-10 catalysts for high-yield synthesis of α,β-epoxy ketones

Developing highly active heterogeneous catalysts for the efficient construction of valuable building blocks is of great importance to synthetic chemistry. For this purpose, a mesoporous zeolite ETS-10 (METS-10) is synthesized by using a mesoscale silane surfactant as a template and applied to achieve highly efficient syntheses of α,β-epoxy ketones by employing simple alkenes and aldehydes as starting materials. The high activity of the METS-10 catalyst is attributed to its unique porous structure and basicity. Electron paramagnetic resonance characterization results and theoretical calculation experimental data reveal that the strong basic sites on METS-10 catalyst can activate the reaction substrate and intermediate. In addition, the mesopores in METS-10 catalyst benefit the mass transfer and further improve the catalytic activity. Mesoporous zeolite ETS-10 is synthesized by using mesoscale silane surfactant as a template and applied to the highly efficient synthesis of α,β-epoxy ketones by employing simple alkenes and aldehydes as starting materials. The high activity of the mesoporous ETS-10 catalyst is attributed to its unique porous structure and basicity.