61012-31-5

Basic information

• Product Name: Ferulamide
• Synonyms: 2-PropenaMide, 3-(4-hydroxy-3-Methoxyphenyl)-, (2E)-
• CAS NO: 61012-31-5
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193
• Mol File: 61012-31-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 435.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.257±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.85±0.31(Predicted)
• CAS DataBase Reference: Ferulamide(CAS DataBase Reference)
• NIST Chemistry Reference: Ferulamide(61012-31-5)
• EPA Substance Registry System: Ferulamide(61012-31-5)

Safety Data

• Hazardous Substances Data: 61012-31-5(Hazardous Substances Data)

Usage

General Description

Ferulamide is a chemical compound that belongs to the class of amides and is derived from ferulic acid. It is commonly found in plants and is known for its antioxidant properties. Ferulamide has shown potential as a natural sunscreen agent, as it can absorb ultraviolet radiation and protect the skin from sun damage. Additionally, it also has anti-inflammatory and anti-cancer properties, making it a subject of interest for pharmaceutical and cosmetic industries. Research on ferulamide continues to explore its potential applications in skincare products and medical treatments.

Upstream product

• 2596-47-6 (E)-3-(4-acetoxy-3-methoxyphenyl)acrylic acid 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 50906-12-2 4-acetoxy-3-methoxycinnamoyl chloride 

Downstream Products

• 99075-98-6 3-(4-hydroxy-3-methoxyphenyl)propanamide 

Relevant articles and documents

A Thorough Study on the Photoisomerization of Ferulic Acid Derivatives

A thorough study on the (E) to (Z) photoisomerization of ferulic acid derivatives (esters, amides of all types, and ketones) was carried out. At the photostationary state, only aliphatic or benzylic tertiary amides reach a nearly complete conversion of (E) isomers into the (Z) ones, whereas for esters, primary and secondary amides or aromatic tertiary amides mixtures of (Z)/(E) ranging from 7 : 93 to 72 : 28 are observed. Ketones show rather limited photoisomerization. However, (Z) ketones may be obtained by the reaction of organometal compounds with an isomerized (Z) Weinreb amide.

Reactions of dehydrodiferulates with ammonia

Lignocellulosic materials derived from forages and agricultural residues are potential sustainable resources for production of bioethanol or other liquid biofuels. However, the natural recalcitrance of such materials to enzymatic hydrolysis is a major obstacle in their efficient utilization. In grasses, much of the recalcitrance is associated with ferulate cross-linking in the cell wall, i.e., with polysaccharide-polysaccharide cross-linking that results from ferulate dehydrodimerization or with lignin-polysaccharide cross-linking that results from the incorporation of (polysaccharide-bound) ferulates or diferulates into lignin, mainly via free-radical coupling reactions. Many pretreatment methods have been developed to address recalcitrance, with ammonia pretreatments in general, and the AFEX (Ammonia Fiber Expansion) process in particular, among the more promising methods. In order to understand the polysaccharide liberating reactions involved in the cleavage of diferulate cell wall cross-links during AFEX pretreatment, reaction products from five esters modeling the major diferulates in grass cell walls treated under AFEX-like conditions were separated and characterized by NMR and HR-MS. Results from this study indicate that, beyond the anticipated amide products, a range of degradation products derive from an array of cleavage and substitution reactions, and reveal various pathways for incorporating ammonia-based nitrogen into biomass.