61019-03-2

Basic information

• Product Name: Benzene, 5-methoxy-1,3-dimethyl-2-nitro-
• Synonyms: 5-methoxy-1,3-dimethyl-2-nitrobenzene;Anisole, 3,5-dimethyl-4-nitro-;Benzene, 5-methoxy-1,3-dimethyl-2-nitro-
• CAS NO: 61019-03-2
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.18854
• Mol File: 61019-03-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 48-50 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 295.6°Cat760mmHg
• Flash Point: 135.9°C
• Appearance: /
• Density: 1.148g/cm³
• Vapor Pressure: 0.00267mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Benzene, 5-methoxy-1,3-dimethyl-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 5-methoxy-1,3-dimethyl-2-nitro-(61019-03-2)
• EPA Substance Registry System: Benzene, 5-methoxy-1,3-dimethyl-2-nitro-(61019-03-2)

Safety Data

• Hazardous Substances Data: 61019-03-2(Hazardous Substances Data)

Usage

General Description

Benzene, 5-methoxy-1,3-dimethyl-2-nitro- is a chemical compound with the molecular formula C9H11NO3. It is a nitro derivative of 5-methoxy-1,3-dimethylbenzene, and is commonly used in organic synthesis and pharmaceutical research. The compound has a nitro group and a methoxy group attached to the benzene ring, giving it potential applications in the production of various organic compounds. Its chemical structure and properties make it useful for creating new molecules with specific properties and is of interest to researchers in the pharmaceutical and chemical industries.

InChI:InChI=1/C9H11NO3/c1-6-4-8(13-3)5-7(2)9(6)10(11)12/h4-5H,1-3H3

Upstream product

• 75-52-5 nitromethane 
• 5344-97-8 3,5-dimethyl-4-nitrophenol 
• 584-08-7 potassium carbonate 
• 80-48-8 methyl p-toluene sulfonate 
• 70547-87-4 2,6-dimethyl-4-hydroxybenzaldehyde 
• 19447-00-8 4-methoxy-2,6-dimethylbenzylaldehyde 
• 7697-37-2 nitric acid 
• 874-63-5 3,5-dimethylmethoxybenzene 
• 74-88-4 methyl iodide 
• 865-48-5 sodium t-butanolate 
• 75-65-0 tert-butyl alcohol 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 102440-03-9 2,6-dimethyl-4-methoxyaniline hydrochloride 
• 142-04-1 aniline hydrochloride 
• 391201-50-6 bis-(4-methoxy-2,6-dimethyl-phenyl)-diazene-N,N'-dioxide 
• 94521-98-9 acetic acid-(4-methoxy-2,6-dimethyl-anilide) 
• 34743-49-2 4-methoxy-2,6-dimethylaniline 

Relevant articles and documents

No-caririeir-added 11C-labelling of benzenoid compounds in ring positions by condensation of nitro-[11C]methane with pyrylium salts

A new synthesis is described for three no-carrier-added nitro-[1-11C] benzenes 3a-c by condensation of nitro-[11C]methane (1) with the appropriate pyrylium salts 2a-c in the presence of a base such as t-BuOK in t-BuOH. For synthesizing 4-nitro-[4-11C]anisole (3a), tetrabutylammonium fluoride was successfully used as an auxiliary base. The best results were obtained in the synthesis of 3a. The conversion of 1 with 4-methoxypyrylium perchlorate (2a) yielded 3a of a radiochemical purity of up to 82% and a mean specific radioactivity of 30 GBq/μmol (0.8 Ci/μmol) within 20 min. Related to 1, the reproducible radiochemical yields of 3a are in the range of 77 ± 5% (decay-corrected). 2,6-Dimethyl-4-methoxy-nitro[1-11C]benzene (3b) was prepared by reaction of 1 with 2,6-dimethyl-4-methoxypyrylium perchlorate (2b) in radiochemical yields of about 37% (decay-corrected) within 10 min. 2-Nitro-[2-11C]mesitylene (3c) was obtained by condensation of 1 with 2,4,6-trimethylpyrylium tetrafluoroborate (2c) in radiochemical yields of about 29% (decay-corrected) within 20 min. 13C/11C Co-labelling experiments were carried out in order to confirm the identity of 3a-c and the position of the label.

Amidinoureas substituted in both the urea and amidino nitrogen positions

A method of inducing blood pressure reduction in humans and mammals by administering 2,6-disubstituted phenyl N-alkyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, acyloxy or halo acyloxy group and a novel class of amidinourea compounds having pharmaceutical uses, including blood pressure lowering activity.