611-03-0

Basic information

• Product Name: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE
• Synonyms: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE;2,4-bis(azanyl)benzoic acid
• CAS NO: 611-03-0
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 225.07
• Mol File: 611-03-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 140°C
• Boiling Point: 274.61°C (rough estimate)
• Flash Point: 196.7°C
• Appearance: /
• Density: 1.2804 (rough estimate)
• Vapor Pressure: 3.61E-07mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 5.60±0.10(Predicted)
• CAS DataBase Reference: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE(611-03-0)
• EPA Substance Registry System: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE(611-03-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 611-03-0(Hazardous Substances Data)

Usage

Description

2,4-Diaminobenzoic Acid Dihydrochloride is an organic compound with the chemical formula C7H8N2O2·2HCl. It is a white crystalline solid that is soluble in water and slightly soluble in organic solvents. 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE is characterized by the presence of two amino groups at the 2nd and 4th positions of the benzene ring, and two hydrochloride ions attached to it.

Uses

Used in Pharmaceutical Industry:
2,4-Diaminobenzoic Acid Dihydrochloride is used as a reagent for the optimization of quinazolinones, which are compounds with anti-tubercular properties. It plays a crucial role in the development of new drugs to combat tuberculosis, a disease that continues to be a significant global health concern.
Used in Biochemical Research:
In the field of biochemical research, 2,4-Diaminobenzoic Acid Dihydrochloride is utilized in the preparation of DNA Polymerase III inhibitors. DNA Polymerase III is an enzyme involved in DNA replication, and its inhibition can be useful in studying the mechanisms of DNA synthesis and in the development of antiviral and anticancer drugs.
Overall, 2,4-Diaminobenzoic Acid Dihydrochloride is a versatile compound with applications in both the pharmaceutical industry and biochemical research, contributing to the development of new drugs and the understanding of fundamental biological processes.

InChI:InChI=1/C7H8N2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,8-9H2,(H,10,11)

Upstream product

• 619-17-0 4-Nitroanthranilic acid 
• 5466-84-2 4-nitrophthalic anhydride 
• 610-27-5 4-nitrophthalic acid 
• 85-44-9 phthalic anhydride 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 6282-12-8 2,4-diacetylaminotoluene 
• 1204-29-1 1-ethyl-2,4-dinitrobenzene 
• 73748-78-4 2,4-diacetylaminobenzoic acid 

Downstream Products

• 1606159-00-5 C₈H₇N₃OS 
• 81115-53-9 2-acetylamido-4-methyl-5-nitrobenzoic acid 
• 59674-85-0 7-aminoquinazoline-2,4(1H,3H)-dione 
• 619-17-0 4-Nitroanthranilic acid 
• 100076-14-0 7-amino-2-isopropylamino-4H-3,1-benzoxazin-4-one 
• 50-84-0 2,4 dichlorobenzoic acid 

Relevant articles and documents

Synthesis method of 2,4-diaminobenzoic acid

The present invention discloses a synthesis method of 2,4-diaminobenzoic acid, and belongs to the field of chemical synthesis. The synthesis method comprises the following steps: using phthalic anhydride as a raw material; adding concentrated sulfuric acid and fuming nitric acid to generate 4-nitrophthalic acid; adding acetic anhydride into the 4-nitrophthalic acid and heating until the solid is completely dissolved; washing ether to obtain 4-nitro phthalic anhydride; mixing and heating the 4-nitro phthalic anhydride with urea; evacuating a reaction system; then adding hydrochloric acid to obtain 4-nitro-2-formyl acetaminobenzoic acid; obtaining 2-amino-4-nitrobenzoic acid under the conditions of a sodium hypochlorite solution and an ice bath; and finally refluxing with absolute ethanol, and adding an ammonium sulfide solution to finally produce 2,4-diaminobenzoic acid by using microwave heating and other conditions.

2,4-Bis(octadecanoylamino)benzenesulfonic acid sodium salt as a novel scavenger receptor inhibitor with low molecular weight

In order to investigate the effect of the fixation of the orientations of the two long chains, three types of novel derivatives of scavenger receptor inhibitor 1 were synthesized, and their biological activities were evaluated. Among the novel derivatives

Transition metal complexes as dye forming catalysts in hair coloring compositions

A hair coloring composition comprising a first composition which comprises: (a) a dye forming transition metal salt or complex; which is first applied to the hair; and a second composition which comprises the following two compositions which are mixed just prior to application to the hair: (a) a composition comprising a water-soluble peroxygen oxidizing agent; and (b) a composition comprising one or more oxidative hair coloring agents selected from the group consisting of an aromatic diamine, an aminophenol, a polyhydric phenol a catechol and mixtures thereof.