61151-96-0

Basic information

• Product Name: ethyl (5-Methyl-2-phenyloxazol-4-yl)carboxylate
• Synonyms: ethyl (5-Methyl-2-phenyloxazol-4-yl)carboxylate;5-Methyl-2-phenyl-oxazole-4-carboxylic acid ethyl ester
• CAS NO: 61151-96-0
• Molecular Formula: C₁₃H₁₃NO₃
• Molecular Weight: 231.25
• EINECS: -0
• Mol File: 61151-96-0.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl (5-Methyl-2-phenyloxazol-4-yl)carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (5-Methyl-2-phenyloxazol-4-yl)carboxylate(61151-96-0)
• EPA Substance Registry System: ethyl (5-Methyl-2-phenyloxazol-4-yl)carboxylate(61151-96-0)

Safety Data

• Hazardous Substances Data: 61151-96-0(Hazardous Substances Data)

Upstream product

• 15933-07-0 Ethyl 2-oxobutanoate 
• 100-47-0 benzonitrile 
• 51655-71-1 2-phenyl-5-methyl-4-oxazolecarboxylic acid chloride 
• 64-17-5 ethanol 
• 2009-97-4 ethyl 2-diazo-3-oxobutanoate 
• 21486-57-7 2-(amino-phenyl-methylene)-3-oxo-butyric acid ethyl ester 
• 141-97-9 ethyl acetoacetate 
• 4341-76-8 Ethyl 2-butynoate 
• 100-46-9 benzylamine 
• 2999-46-4 Ethyl isocyanoacetate 
• 108-86-1 bromobenzene 
• 32968-44-8 5-Methyl-4-oxazolcarbonsaeure-ethylester 
• 104690-31-5 ethyl 2-iodo-3-oxobutanoate 
• 1144520-57-9 ethyl 2-chloro-5-methyloxazole-4-carboxylate 

Downstream Products

• 1144520-66-0 C₁₂H₁₂N₄O₂ 
• 51655-72-2 5-methyl-2-phenyl-oxazole-4-carboxylic acid amide 
• 51655-71-1 2-phenyl-5-methyl-4-oxazolecarboxylic acid chloride 
• 80022-56-6 ethyl 2-phenyl-5-phenylthiomethyloxazole-4-carboxylate 
• 80022-53-3 ethyl 2-phenyl-5-phenoxymethyloxazole-4-carboxylate 
• 80022-62-4 2-Phenyl-5-phenylsulfanylmethyl-oxazole-4-carboxylic acid 
• 80022-59-9 2-phenyl-5-phenoxymethyloxazole-4-carboxylic acid 
• 80022-68-0 2-Phenyl-10H-1-oxa-9-thia-3-aza-benzo[f]azulen-4-one 
• 80022-65-7 2-phenyl-4,10-dihydro-4-oxo<1>benzoxepino<4,3-d>oxazole 
• 132451-15-1 N-methyl-N-<(5-methyl-2-phenyl-4-oxazolyl)methyl>-4<(2,4-dioxothiazolidin-5-yl)methyl>benzenesulfonamide 
• 132451-19-5 N-methyl-N-<(5-methyl-2-phenyl-4-oxazolyl)methyl>-4<(2,4-dioxothiazolidin-5-yl)methyl>benzamide 
• 132451-17-3 N-methyl-N-<(5-methyl-2-phenyl-4-oxazolyl)methyl>-4<(2,4-dioxothiazolidin-5-ylidene)methyl>benzamide 
• 141200-22-8 5-{4-[(E)-3-(5-Methyl-2-phenyl-oxazol-4-yl)-acryloyl]-benzyl}-thiazolidine-2,4-dione 
• 132451-31-1 4-methylaminocarbonyl>benzaldehyde 

Relevant articles and documents

Electrochemical Iodine-Mediated Oxidation of Enamino-Esters to 2H-Azirine-2-Carboxylates Supported by Design of Experiments

An electrochemical iodine-mediated transformation of enamino-esters for the synthesis of 2H-azirine-2-carboxylates is presented. In addition, a thermic conversion of azirines to 4-carboxy-oxazoles in quantitative yield without purification was described.

miRNA biosynthesis inhibitor

The invention provides a compound shown as a formula I, or a conformational isomer thereof, or an optical isomer thereof, or a pharmaceutically acceptable salt thereof. The compound can be tightly combined with related binding proteins in an miRNA biosynthesis process and can effectively inhibit the synthesis of miRNA-21. The prepared active compound provided by the invention can be used as an miRNA-21 inhibitor, and further as a potential drug for treating malignant tumors. The formula I is shown in the description.

Convenient route to trisubstituted oxazoles via a copper-catalysed tandem oxidative cyclisation by oxygen oxidation

A novel copper-catalysed oxidative cyclisation has been developed for the synthesis of trisubstituted oxazoles, which is thought to proceed through cascade formation of C-N and C-O bonds by oxygen oxidation. The desired products can be obtained from readily available starting materials while avoiding hazardous materials. Therefore, a green synthetic method for the preparation of oxazoles has been found.