61200-60-0

Basic information

• Product Name: 2,5-DICHLOROTHIOPHENE-3-CARBALDEHYDE, 97
• Synonyms: 2,5-Dichlorothiophene-3-carbaldehyde;2,5-DICHLOROTHIOPHENE-3-CARBALDEHYDE, 97;3-Thiophenecarboxaldehyde, 2,5-dichloro-;2,5-Dichloro-3-formylthiophene;2,5-dichloro-3-Thiophenecarboxaldehyde
• CAS NO: 61200-60-0
• Molecular Formula: C₅H₂Cl₂OS
• Molecular Weight: 181.03978
• Mol File: 61200-60-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 24.0-24.5 °C
• Boiling Point: 229.8 °C at 760 mmHg
• Flash Point: 92.8 °C
• Appearance: /
• Density: 1.581 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2,5-DICHLOROTHIOPHENE-3-CARBALDEHYDE, 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DICHLOROTHIOPHENE-3-CARBALDEHYDE, 97(61200-60-0)
• EPA Substance Registry System: 2,5-DICHLOROTHIOPHENE-3-CARBALDEHYDE, 97(61200-60-0)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl
• Hazardous Substances Data: 61200-60-0(Hazardous Substances Data)

Usage

General Description

2,5-Dichlorothiophene-3-carbaldehyde, 97 is a chemical compound with a molecular formula C6H3Cl2OS. It is a yellow to light brown solid that is primarily used in the field of organic synthesis. The compound is frequently utilized as a building block in the production of various pharmaceuticals, agrochemicals, and organic dyes. It is also known for its use as a precursor in the synthesis of heterocyclic compounds and in the development of new materials. Additionally, 2,5-Dichlorothiophene-3-carbaldehyde, 97 is valued for its role in research and development activities within the chemical and pharmaceutical industries.

Upstream product

• 3172-52-9 2,5-diclorothiophene 
• 68-12-2 N,N-dimethyl-formamide 
• 4885-02-3 Dichloromethyl methyl ether 
• 14345-98-3 2-chlorothiophene-3-carboxaldehyde 

Downstream Products

• 5425-39-8 2,5-dichloro-thiophene-3-carbaldehyde thiosemicarbazone 
• 36157-41-2 2,5-dichlorothiophene-3-carboxylic acid 

Relevant articles and documents

Continuous flow magnesiation of functionalized heterocycles and acrylates with TMPMgCl·LiCl

A flow procedure for the metalation of functionalized heterocycles (pyridines, pyrimidines, thiophenes, and thiazoles) and various acrylates using the strong, non-nucleophilic base TMPMgCl·LiCl is reported. The flow conditions allow the magnesiations to be performed under more convenient conditions than the comparable batch reactions, which often require cryogenic temperatures and long reaction times. Moreover, the flow reactions are directly scalable without further optimization. Metalation under flow conditions also allows magnesiations that did not produce the desired products under batch conditions, such as the magnesiation of sensitive acrylic derivatives. The magnesiated species are subsequently quenched with various electrophiles, thereby introducing a broad range of functionalities. Go with the flow: Flow conditions allow a practical metalation of functionalized heterocycles and various acrylates in the presence of the base TMPMgCl·LiCl (TMP=2,2,6,6-tetramethylpiperidyl). More convenient temperatures and very fast reaction times can usually be achieved by applying the flow conditions. Sensitive acrylic derivatives can be magnesiated under flow conditions. Furthermore, the flow reactions are readily scalable without further optimization.

Composition for preventing or treating ischemic disease

-

New imidazole anti-fungal agents derived from benzothiophene. Part II

1-thienyl)methyl>-1H-imidazoles 22, 1-thien-3-yl)(thienyl)methyl>-1H-imidazoles 25 and 1-thien-3-yl)methyl>-1H-imidazoles 28 have been synthesized and tested for anti-fungal activity.All compounds showed good activity against a broad spectrum of fungi (yeasts, dermatophytes).