61485-11-8

Basic information

• Product Name: 1-Pentanone, 1-(2-aminophenyl)-
• Synonyms: o-Aminophenyl-n-butylketon;2-Amino-n-valerophenon;2'-Aminobutyrophenon
• CAS NO: 61485-11-8
• Molecular Formula: C11H15NO
• Molecular Weight: 177.246
• Mol File: 61485-11-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 150-153 °C(Press: 0.1 Torr)
• Density: 1.025±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Pentanone, 1-(2-aminophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanone, 1-(2-aminophenyl)-(61485-11-8)
• EPA Substance Registry System: 1-Pentanone, 1-(2-aminophenyl)-(61485-11-8)

Safety Data

• Hazardous Substances Data: 61485-11-8(Hazardous Substances Data)

Upstream product

• 1343047-78-8 1-(2-aminophenyl)pentan-1-ol 
• 1885-29-6 anthranilic acid nitrile 
• 551-93-9 2-aminoacetophenone 
• 103529-16-4 2-[(trimethylsilyl)ethynyl]aniline 
• 52670-38-9 2-ethynylaniline 
• 615-43-0 2-iodophenylamine 
• 944115-39-3 C₁₁H₁₃NO 
• 71-23-8 propan-1-ol 
• 552-89-6 2-nitro-benzaldehyde 
• 529-23-7 o-aminobenzaldehyde 
• 693-03-8 n-butyl magnesium bromide 
• 109-72-8 n-butyllithium 

Downstream Products

• 197163-72-7 4-n-butyl-2-phenylquinazoline 
• 25855-20-3 2-phenylquinazoline 
• 1350934-77-8 ethyl 4-butyl-2-phenylquinoline-3-carboxylate 

Relevant articles and documents

Copper-Catalyzed Chemoselective Cyclization Reaction of 2-Isocyanoacetophenone: Synthesis of 4-Hydroxyquinoline Compounds

A copper-catalyzed intramolecular cyclization reaction of 2-isocyanoacetophenone derivatives to afford 4-hydroxyquinolines chemoselectively is described. The transformation proceeds through enol tautomerism and a subsequent C-C bond formation. Compared to previous methods, this study provides a new protocol for the construction of 4-hydroxyquinoline compounds from functionalized isocyanides under mild conditions.

Chemoselective Alkylation of Aminoacetophenones with Alcohols by Using a Palladacycle-Phosphine Catalyst

The development of efficient and environmentally benign palladacycle-phosphine catalyzed process to enable the formation of chemoselective C-alkylated or N-alkylated aminoacetophenones with alcohols is described. This methodology proved to be tunable by variation of the base and the temperature, which allows for the isolation of structurally diverse C-alkylated and N-alkylated aminoacetophenones. Moreover, this methodology has been applied to the synthesis of biologically and industrially important donepezil.

SYNTHESIS OF DIINDOLYLMETHANES AND INDOLO[3,2-B]CARBAZOLES, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Described is a method to make diindolylmethanes and indolyl/pyrrolylmethanes, The method includes the steps of contacting an ether comprising an arylpropargyl moiety and an amine-protected, substituted or unsubstituted aniline moiety with a substituted or