6149-48-0

Basic information

• Product Name: ethyl ester of 7-hydroxyheptanoic acid
• Synonyms: ethyl ester of 7-hydroxyheptanoic acid
• CAS NO: 6149-48-0
• Molecular Formula: C₉H₁₈O₃
• Molecular Weight: 174.23742
• Mol File: 6149-48-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.31g/cm³
• Refractive Index: 1.634
• CAS DataBase Reference: ethyl ester of 7-hydroxyheptanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl ester of 7-hydroxyheptanoic acid(6149-48-0)
• EPA Substance Registry System: ethyl ester of 7-hydroxyheptanoic acid(6149-48-0)

Safety Data

• Hazardous Substances Data: 6149-48-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C21H22N4O4S/c1-3-29-16-10-8-15(9-11-16)23-19(26)12-18-20(27)24-21(30-18)25-22-13-14-6-4-5-7-17(14)28-2/h4-11,13,18H,3,12H2,1-2H3,(H,23,26)(H,24,25,27)/b22-13+

Upstream product

• 502-42-1 cycloheptanone 
• 33018-91-6 7-ethoxy-7-oxoheptanoic acid 
• 64-17-5 ethanol 
• 7664-93-9 sulfuric acid 
• 29823-18-5 ethyl 7-bromoheptanoate 
• 22054-13-3 7-hydroxyheptanal 
• 627-27-0 homoalylic alcohol 
• 201230-82-2 carbon monoxide 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 25118-23-4 ethyl 6-heptenoate 
• 120-92-3 cyclopentanone 
• 108-94-1 cyclohexanone 
• 694-54-2 tetrahydro-2H-2-pyranol 
• 821-57-8 7-chloroheptanoic acid 

Downstream Products

• 29823-18-5 ethyl 7-bromoheptanoate 
• 539-87-7 oxocan-2-one 
• 3990-05-4 ethyl 6-formylhexanoate 
• 25118-23-4 ethyl 6-heptenoate 
• 1070-64-0 6,8-dichlorooctanoic acid ethyl ester 
• 77744-45-7 7-((tert-butyldimethylsilyl)oxy)heptanoic acid 
• 1072090-99-3 (2S,3S,4E)-2-((1E,3E,5S)-6-{(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]oxiran-2-yl}-1,5-dimethylhexa-1,3-dien-1-yl)-1,3-dimethyl-12-oxaazacyclododec-4-en-6-yl acetate 
• 1072091-39-4 (9E,11S,12S)-12-[(1E)-3-benzyloxy-1-methylprop-1-en-1-yl]-8-{[tert-butyl(dimethyl)silyl]oxy}-1,1'-dimethylazacyclododec-9-en-2-one 
• 1072091-37-2 N-{(1S,2E)-4-(benzyloxy)-1-[(1S,2E)-3-iodo-1-methylprop-2-en-1-yl]-2-methylbut-2-en-1-yl}-7-hydroxy-N-methylheptanamide 
• 1072091-40-7 C₂₄H₃₄INO₃ 
• 1072091-41-8 C₂₄H₃₅NO₃ 
• 1072091-44-1 (2S,3S,4E)-1,3-dimethyl-2-[(1E)-1-methylbuta-1,3-dien-1-yl]-12-oxoazacylododec-4-en-6-yl acetate 
• 1072091-45-2 C₁₈H₂₉NO₂ 
• 65351-69-1 7-hydroxy-heptanoic acid hydrazide 

Relevant articles and documents

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Synthesis and biological evaluation of aziridin-1-yl oxime-based vorinostat analogs as anticancer agents

The suberoyl anilide hydroxamic acid (vorinostat) analogs with the aziridin-1-yl oxime moiety as a possible metal chelating functionality have been synthesized. Their biological activity and stability under physiological conditions have been evaluated. Although some of the synthesized compounds demonstrated high antiproliferative activity against human HT1080 fibrosarcoma (HT1080, IC50 0.3-7.7 μM) comparable to vorinostat (HT1080, IC50 2.4 μM), they showed only weak histone deacetylase inhibition activity in HeLa cell line extracts.

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