627-27-0 Usage
Description
3-Buten-1-ol is a homoallyl alcohol. It is employed in a study of the Mn-catalyzed hydrohydrazination of olefins. It is also used in a study of the conversion of propargylic acetates to ethers catalyzed by ferric chloride1. It can also be used as a starting reagent in asymmetric total synthesis of natural seimatopolide B. It was also used in the synthesis of catalytic bimetallic nanoparticles2.
Chemical Properties
liquid
Uses
Different sources of media describe the Uses of 627-27-0 differently. You can refer to the following data:
1. 3-Buten-1-ol is an aliphatic primary alcohol used as a reagent in organic synthesis.
2. 3-Buten-1-ol is employed in a study of the Mn-catalyzed hydrohydrazination of olefins. Also used in a study of the conversion of propargylic acetates to ethers catalyzed by ferric chloride.
3. Employed in a study of the Mn-catalyzed hydrohydrazination of olefins. Also used in a study of the conversion of propargylic acetates to ethers cataylzed by ferric chloride.
General Description
3-Buten-1-ol is a homoallyl alcohol that can be prepared by the dehydration of 1,4-butanediol using cerium catalyst. The intramolecular hydrogen bonding of 3-buten-1-ol has been studied using FT-IR and 1H NMR spectroscopic data. Its microwave spectrum has been recorded and analyzed. The alkylation reaction of 3-buten-1-ol using titanium-organoaluminum system has been studied. Its gas-phase enthalpy of formation has been reported to be -147.3 ± 1.8kJ mol-1.
Synthesis
The synthesis of?3-Buten-1-ol is as follows:After adding 24.3 g (1 mol) of magnesium turnings, 50 g of diethyl ether and 1 ml of dibromoethane in a 500 mL four-necked flask,A solution of 62.5 g of vinyl chloride (1 mol) dissolved in 200 g of diethyl ether was added dropwise to magnesium and diethyl ether, and the micro reflux was controlled, and the dropwise addition was completed, and the mixture was kept under a micro reflux for 2 hours, and the temperature was lowered to -5 °C;Then 44 g (1 mol) of ethylene oxide was dissolved in 60 g of diethyl ether. Ethylene oxide is added dropwise to the vinylmagnesium chloride solution prepared above, control the temperature -5-5 degrees, and stir at this temperature for 1 hour. Sampling gas phase analysis until the reaction is complete; pour the reaction solution into a 1000 mL beaker, Add 200mL of ice water and add ammonium chloride until the residual magnesium disappears. Control the temperature 0-10 ° C, stir for 1 hour after the addition, add salt to saturation, static layering. The organic layer was separated and washed twice with 100 ml of saturated brine, and a polymerization inhibitor was added. The product is subjected to rectification to obtain 53 g of 3-buten-1-ol, and the content is 99.2%. The yield was 73.6%.
Check Digit Verification of cas no
The CAS Registry Mumber 627-27-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 627-27:
(5*6)+(4*2)+(3*7)+(2*2)+(1*7)=70
70 % 10 = 0
So 627-27-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H8O/c1-2-3-4-5/h2,5H,1,3-4H2
627-27-0Relevant articles and documents
A recoverable Pd nanocatalyst for selective semi-hydrogenation of alkynes: Hydrogenation of benzyl-propargylamines as a challenging model
Uberman, Paula M.,Costa, Natalia J. S.,Philippot, Karine,C. Carmona, Rafaela,Dos Santos, Alcindo A.,Rossi, Liane M.
, p. 4566 - 4574 (2014)
We describe a recyclable heterogeneous palladium nanocatalyst for the selective hydrogenation of alkynes to alkenes. The catalyst was prepared through the decomposition of the organometallic precursor Pd2(dba)3 over a magnetic support, obtaining well-dispersed Pd nanoparticles that formed exclusively on the support surface, with average diameter of 3.5 ± 0.8 nm. The catalytic activity was investigated in the hydrogenation reactions of alkenes and alkynes, and the chemo- and stereoselectivity were evaluated in the hydrogenation of benzyl-propargylamines. The catalyst is highly selective in performing semi-hydrogenation reactions under mild conditions and short reaction times, with good overall yields. Furthermore, it can be easily recovered and recycled, with no leaching of palladium detected, and activities and selectivity retained over multiple reaction cycles. This journal is
Selective production of 1,3-butadiene from 1,3-butanediol over Y2Zr2O7 catalyst
Matsuda, Asami,Matsumura, Yoshitaka,Sato, Satoshi,Yamada, Yasuhiro
, p. 1651 - 1658 (2021/07/21)
The vapor-phase dehydration of 1,3-butanediol (1,3-BDO) to produce 1,3-butadiene (BD) was evaluated over yttrium zirconate, which was prepared through a hydrothermal aging process. 1,3-BDO was initially dehydrated to three unsaturated alcohols, namely 3-buten-2-ol, 3-buten-1-ol, and 2-buten-1-ol, followed by the further dehydration to BD. The catalytic activity of yttrium zirconate was greatly dependent on the calcination temperature. Also, the reaction temperature was one of the important factors to produce BD efficiently. The selectivity to BD was increased with increasing reaction temperature up to 375°C, while coke formation resulted in catalyst deactivation together with by-product formation at higher temperatures. Yttrium zirconate catalyst calcined at 900°C showed a high BD yield of 95% at 375°C and 10 hr on stream.
Preparation method of 3-butene-1-ol
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Paragraph 0009-0013, (2020/10/05)
The invention relates to a preparation method of 3-butene-1-ol. Ethyl acetate is used as a solvent, allyl bromide, zinc powder, formaldehyde and ammonium chloride are used as raw materials, copper salt is used as a catalyst, and a reaction product is 3-butene-1-ol. The reaction yield is greater than 87%, and the purity is greater than 99%. In order to overcome the defects in the prior art, the catalyst is added, so that the reaction time is greatly shortened; a distillation method is used for replacing multiple times of extraction treatment of the reaction water phase, the operation is easierand more convenient, and the cost is greatly reduced; and an environment-friendly organic matter is used as the solvent, and the green and environment-friendly production concept is met.