61612-37-1

Basic information

• Product Name: methyl [3-(1-hydroxyethyl)-2,2-dimethylcyclobutyl]acetate
• CAS NO: 61612-37-1
• Molecular Formula: C₁₁H₂₀O₃
• Molecular Weight: 200.2747
• Mol File: 61612-37-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 255.5°C at 760 mmHg
• Flash Point: 95.1°C
• Density: 1.001g/cm³
• Vapor Pressure: 0.00246mmHg at 25°C
• Refractive Index: 1.454
• CAS DataBase Reference: methyl [3-(1-hydroxyethyl)-2,2-dimethylcyclobutyl]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl [3-(1-hydroxyethyl)-2,2-dimethylcyclobutyl]acetate(61612-37-1)
• EPA Substance Registry System: methyl [3-(1-hydroxyethyl)-2,2-dimethylcyclobutyl]acetate(61612-37-1)

Safety Data

• Hazardous Substances Data: 61612-37-1(Hazardous Substances Data)

Upstream product

• 17879-35-5 cis-pinonic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 52305-35-8 methyl 2-[(1R,3R)-3-acetyl-2,2-dimethylcyclobutyl]acetate 
• 16978-11-3 methyl [(1SR,3SR)-3-acetyl-2,2-dimethylcyclobutyl]acetate 
• 473-72-3 (1'R,3'R)-2-(3'-acetyl-2',2'-dimethylcyclobutyl)acetic acid 

Relevant articles and documents

Carboxy mediated stereoselective reduction of ketones with sodium triacetoxyborohydride: Synthesis of novel 3,4-fused tetrahydropyran and tetrahydrofuran prolines

In the presence of a carboxyl group positioned for participation, NaBH(OAc)3 will reduce the usually unreactive ketones in a stereoselective manner. This reaction was applied in a key step to prepare precursors 7 and 15 toward the title compounds 1 and 2. These results are consistent with the exchange of one of the acetoxy groups in the reducing agent with the carboxy group followed by intramolecular delivery of the hydride.