61638-04-8

Basic information

• Product Name: 1,4-DIMETHOXY-2-METHYLTHIOBENZENE
• Synonyms: 1,4-DIMETHOXY-2-METHYLTHIOBENZENE;2,5-dimethoxy-4-(methylthio)benzaldehyde(SALTDATA: FREE);2,5-dimethoxy-4-(methylsulfanyl)benzaldehyde
• CAS NO: 61638-04-8
• Molecular Formula: C₁₀H₁₂O₃S
• Molecular Weight: 184.25538
• Mol File: 61638-04-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 357.5°C at 760 mmHg
• Flash Point: 176.3°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 2.72E-05mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 1,4-DIMETHOXY-2-METHYLTHIOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIMETHOXY-2-METHYLTHIOBENZENE(61638-04-8)
• EPA Substance Registry System: 1,4-DIMETHOXY-2-METHYLTHIOBENZENE(61638-04-8)

Safety Data

• Hazardous Substances Data: 61638-04-8(Hazardous Substances Data)

Usage

Chemical class

Thioether

Derivative of

Benzene

Common uses

Synthesis of pharmaceuticals
Synthesis of agricultural chemicals
Intermediate in production of insecticides and herbicides

Potential applications

Antitumor agent (inhibits cancer cell growth)

Hazardous nature

Considered a hazardous chemical

Handling precautions

Should be handled with caution in a controlled laboratory setting

InChI:InChI=1/C10H12O3S/c1-12-8-5-10(14-3)9(13-2)4-7(8)6-11/h4-6H,1-3H3

Upstream product

• 2570-42-5 2-(methylthio)-1,4-dimethoxybenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 4991-65-5 tioxolone 
• 1483-27-8 2,5-dimethoxythiophenol 
• 150-78-7 1,4-dimethoxybezene 
• 93-61-8 N-methyl-N-phenylformamide 
• 4885-02-3 Dichloromethyl methyl ether 
• 74-93-1 methylthiol 
• 31558-41-5 4-bromo-2,5-dimethoxybenzaldehyde 

Downstream Products

• 61638-05-9 1-(2,5-dimethoxy-4-methylthiophenyl)-2-nitro-1-propene 
• 61638-09-3 2,5-dimethoxy-4-methylthiophenethylamine 
• 756766-56-0 2-amino-1-(2,5-dimethoxy-4-methylthiophenyl)butane 
• 61638-07-1 2,5-dimethoxy-4-(methylthio)amphetamine 
• 849919-85-3 N-formyl-1-(2,5-dimethoxy-4-methylthiophenyl)-2-aminobutane 
• 849919-81-9 N-formyl-1-(2,5-dimethoxy-4-methylthiophenyl)-2-aminopropane 
• 61638-06-0 1,4-Dimethoxy-2-methylsulfanyl-5-((Z)-2-nitro-vinyl)-benzene 
• 69294-31-1 1-(2,5-dimethoxy-4-methylthiophenyl)-2-nitro-1-butene 

Relevant articles and documents

Accelerated Fmoc solid-phase synthesis of peptides with aggregation-disrupting backbones

In this work, we describe an accelerated solid-phase synthetic protocol for ordinary or difficult peptides involving air-bath heating and amide protection. For the Hmsb-based backbone amide protection, an optimized acyl shift condition using 1,4-dioxane w

FACILE SYNTHESIS OF ALKYLTHIOBENZALDEHYDES

Alkoxyl alkylthiobenzaldehydes can be readily prepared from the corresponding bromobenzaldehydes and the sodium salt of primary mercaptanes in DMF.

Monomethylthio analogues of 1-(2,4,5-trimethoxyphenyl)-2-aminopropane

Regiospecific syntheses of the three monomethylthio analogues of 1-(2,4,5- trimethoxyphenyl)-2-aminopropane are described. The three isomeric amines were evaluated for potential psychotomimetic potency using the rabbit hyperthermia assay. Enantiomeric com