61652-81-1

Basic information

• Product Name: 1-DECANESULFONYL CHLORIDE
• Synonyms: 1-DECANESULFONYL CHLORIDE;1-DECANESULPHONYL CHLORIDE;1-Decanesulfonylchloride,98%;1-Decanesulfonic acid chloride;1-Decanesulfonyl chloride,99%
• CAS NO: 61652-81-1
• Molecular Formula: C₁₀H₂₁ClO₂S
• Molecular Weight: 240.79
• Mol File: 61652-81-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 34 °C
• Boiling Point: 310.5°Cat760mmHg
• Flash Point: 141.6°C
• Appearance: /
• Density: 1.065g/cm³
• Vapor Pressure: 0.00109mmHg at 25°C
• Refractive Index: 1.46
• Water Solubility: It reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 1771852
• CAS DataBase Reference: 1-DECANESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-DECANESULFONYL CHLORIDE(61652-81-1)
• EPA Substance Registry System: 1-DECANESULFONYL CHLORIDE(61652-81-1)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3261
• TSCA: Yes
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 61652-81-1(Hazardous Substances Data)

Usage

Description

1-Decanesulfonyl chloride is an organic compound with the chemical formula C10H21ClO2S. It is a white to off-white low melting solid or crystals, which is commonly used as a pharmaceutical intermediate due to its unique chemical properties.

Uses

1. Used in Pharmaceutical Industry:
1-Decanesulfonyl chloride is used as a pharmaceutical intermediate for the synthesis of various drugs. Its chemical structure allows it to be a versatile building block in the development of new pharmaceutical compounds, contributing to the advancement of medical treatments.
2. Used in Organic Synthesis:
In addition to its pharmaceutical applications, 1-Decanesulfonyl chloride is also utilized in organic synthesis for the production of various organic compounds. Its reactivity and functional groups make it a valuable component in the synthesis of specialty chemicals and materials.

InChI:InChI=1/C10H21ClO2S/c1-2-3-4-5-6-7-8-9-10-14(11,12)13/h2-10H2,1H3

Upstream product

• 5349-20-2 1-thiocyanatodecane 
• 10496-18-1 didecyl disulfide 
• 112-29-8 1-bromo dodecane 

Downstream Products

• 307-51-7 perfluorodecane sulfonylfluoride 
• 98511-51-4 (4-Decansulfonamidobenzoyl)hydrazin 
• 1612796-79-8 N'-(decylsulfonyloxy)-4-nitrobenzimidamide 
• 104-72-3 decylbenzene 
• 131803-81-1 N-decanesulfonyl-L-phenylalanine 
• 100980-25-4 Aethyl-4-decansulfonamidobenzoat 
• 101426-30-6 decane-1-sulfonanilide 

Relevant articles and documents

Oxidation of disulfides with electrophilic halogenating reagents: Concise methods for preparation of thiosulfonates and sulfonyl halides

The reaction of aromatic or benzylic disulfides with 2.5 equiv of Selectfluor in acetonitrile/water (10:1) at room temperature efficiently produced the corresponding thiosulfonates. Conversely, the reaction of disulfides with 6.5 equiv of Selectfluor or thiosulfonates with 4.5 equiv of Selectfluor in refluxing acetonitrile/water (10:1) provided sulfonyl fluorides in high yields. Accufluor and FP-T300 are also effective in preparing sulfonyl fluorides from disulfides under the similar reaction conditions. Sulfonyl chlorides or sulfonyl bromides were effectively obtained from the reaction of disulfides with 6 equiv of either N-chlorosuccinimide or N-bromosuccinimide in acetonitrile/water (10:1) at room temperature. Some other electrophilic chlorinating or brominating reagents are also able to be used instead of N-chlorosuccinimide or N-bromosuccinimide for the syntheses of sulfonyl halides from disulfides. These reactions of disulfides with electrophilic halogenating reagents are convenient methods to prepare thiosulfonates and sulfonyl halides.

Method for making alkanesulphonyl chlorides

In the process according to the invention for the manufacture of an alkanesulphonyl chloride RCH2—SO2Cl by oxidative chlorolysis of the corresponding mercaptan RCH2—SH, the mercaptan and water are introduced into the reaction mixture in the form of a dispersion of water in the mercaptan. This makes it possible to obtain both an alkanesulphonyl chloride of very good quality and a hydrochloric acid of commercial grade.