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6197-39-3

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  • methyl 1,2,3,6-tetrahydropyridine-5-carboxylate,hydrochloride

    Cas No: 6197-39-3

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6197-39-3 Usage

Description

Methyl 1,2,5,6-Tetrahydropyridine-3-carboxylate Hydrochloride is an organic compound with the molecular formula C6H10NO2·HCl. It is a derivative of tetrahydropyridine, featuring a methyl ester group and a carboxylate group. Methyl 1,2,5,6-Tetrahydropyridine-3-carboxylate Hydrochloride is typically utilized as an intermediate in the synthesis of various pharmaceuticals and chemicals.

Uses

Used in Pharmaceutical Synthesis:
Methyl 1,2,5,6-Tetrahydropyridine-3-carboxylate Hydrochloride is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for further chemical modifications, making it a valuable building block in the development of new drugs.
Used in Chemical Research:
In the field of chemical research, Methyl 1,2,5,6-Tetrahydropyridine-3-carboxylate Hydrochloride serves as a key compound for studying the properties and reactivity of tetrahydropyridine derivatives. This helps researchers understand the underlying mechanisms of various chemical reactions and potentially discover new applications for this class of compounds.
Used in Analytical Chemistry:
Methyl 1,2,5,6-Tetrahydropyridine-3-carboxylate Hydrochloride can be employed as a standard or reference material in analytical chemistry. It can be used to calibrate instruments, validate analytical methods, and ensure the accuracy of measurements related to tetrahydropyridine derivatives.
Used in Quality Control:
In the pharmaceutical industry, Methyl 1,2,5,6-Tetrahydropyridine-3-carboxylate Hydrochloride may be used for quality control purposes. It can help ensure that the synthesized products meet the required specifications and standards, contributing to the overall safety and efficacy of the final drug product.

Check Digit Verification of cas no

The CAS Registry Mumber 6197-39-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,9 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6197-39:
(6*6)+(5*1)+(4*9)+(3*7)+(2*3)+(1*9)=113
113 % 10 = 3
So 6197-39-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO2.ClH/c1-10-7(9)6-3-2-4-8-5-6;/h3,8H,2,4-5H2,1H3;1H

6197-39-3Relevant articles and documents

N-Heteroarylmethyl-5-hydroxy-1,2,5,6-tetrahydropyridine-3-carboxylic acid a novel scaffold for the design of uncompetitive α-glucosidase inhibitors

Long, Sha,Stefani, Francesca Romana,Biondi, Stefano,Ghiselli, Giancarlo,Panunzio, Mauro

, p. 5811 - 5822 (2013/09/12)

Abstract The enzyme α-glucosidase has attracted interest owing to its involvement in the digestive process of carbohydrate, its role in intracellular glycoprotein trafficking, tumorigenesis and viral infection. In this study, several members of a new family of N-heteroarylmethyl substituted azasugars were synthesized and evaluated as α-glucosidase inhibitors. We systematically investigated the effect of different N-substituents as well as the role of hydroxyl and carboxylate moieties on the piperidine ring. The compounds N-heteroarylmethyl-5-hydroxy-1,2,5,6-tetrahydropyridine-3-carboxylic acid emerged as potent α-glucosidase inhibitors. Unlike Acarbose and other clinically relevant α-glucosidase inhibitors, these compounds act through a reversible uncompetitive mechanism of inhibition which make them attractive candidates for drug development.

A General, Selective, High-Yield N-Demethylation Procedure for Tertiary Amines by Solid Reagents in a Convenient Column Chromatography-like Setup

Rosenau, Thomas,Hofinger, Andreas,Potthast, Antje,Kosma, Paul

, p. 541 - 544 (2007/10/03)

(Equation presented) A traditional preparative chromatographic column can be used to achieve quantitative N-demethylation of tertiary N-methylamines and alkaloids. The filling is the crucial part and is loaded with different solid reagents in three reaction zones. The parent compound is charged on the column, and the neat N-demethylated secondary amine leaves the column some minutes later.

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