61977-29-5 Usage
Description
6-CHLOROBENZO[D]ISOXAZOL-3-OL, also known as 6-Chloro-1,2-benzisoxazol-3(2H)-one, is a chemical compound characterized by its gray solid appearance. It is a D-amino acid oxidase reversible inhibitor, which means it can bind to the enzyme D-amino acid oxidase and temporarily inhibit its activity, making it a potentially useful compound in various applications.
Uses
Used in Pharmaceutical Industry:
6-CHLOROBENZO[D]ISOXAZOL-3-OL is used as a pharmaceutical compound for its D-amino acid oxidase inhibitory properties. This characteristic makes it a promising candidate for the development of drugs targeting various medical conditions, as it can potentially modulate the activity of D-amino acid oxidase, which is involved in several biological processes.
Used in Research and Development:
In the field of research and development, 6-CHLOROBENZO[D]ISOXAZOL-3-OL serves as a valuable tool for studying the function and role of D-amino acid oxidase in cellular processes. By reversibly inhibiting the enzyme, researchers can gain insights into its mechanisms of action and explore potential therapeutic applications.
Used in Chemical Synthesis:
As a chemical compound with unique properties, 6-CHLOROBENZO[D]ISOXAZOL-3-OL can be utilized in the synthesis of other related compounds or as an intermediate in the production of various chemical products. Its specific chemical structure and reactivity make it a versatile building block for creating novel molecules with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 61977-29-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,9,7 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 61977-29:
(7*6)+(6*1)+(5*9)+(4*7)+(3*7)+(2*2)+(1*9)=155
155 % 10 = 5
So 61977-29-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H4ClNO2/c8-4-1-2-5-6(3-4)11-9-7(5)10/h1-3H,(H,9,10)
61977-29-5Relevant articles and documents
Chromatography-free, Mitsunobu-triggered heterocyclizations of salicylhydroxamic acids to 3-hydroxybenzisoxazoles
Van Eker, Daniel,Chauhan, Jay,Murphy, William A.,Conlon, Ivie L.,Fletcher, Steven
, p. 5301 - 5303 (2016/11/16)
The Mitsunobu reaction has become one of the most powerful tools to alkylate acidic pronucleophiles. A significant caveat of Mitsunobu chemistry, however, is that the reaction mixture is often plagued with purification problems owing to the phosphine oxide and hydrazine dicarboxylate by-products. In addition to the development of more readily separable Mitsunobu reagents, the product's physicochemical properties may be exploited to facilitate purification. In this regard, we present a swift and efficient preparation of 3-hydroxybenzisoxazoles by the Mitsunobu-triggered heterocyclizations of salicylhydroxamic acids, which can be isolated by an acid–base work-up. As expected, a range of functional groups was compatible with the chemistry.
ARALKYL SUBSTITUTED PIPERIDINE OR PIPERAZINE DERIVATIVES AND THEIR USE FOR TREATING SCHIZOPHRENIA
-
, (2011/06/10)
The present invention discloses an aralkyl substituted piperidine or piperazine derivative and the use of the derivative in preparation of medicaments for treating schizophrenia and correlative psychoneuroses. It is shown by pharmacological tests that the derivative of the present invention has better antischizophrenic effect and less toxicity. Said derivative is a free base or salt of the compound having the following general formula.
Substituted benzisoxazole and benzisothiazole herbicidal agents
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, (2008/06/13)
There are provided substituted benzisoxazole and benzisothiazole compounds having the structural formula I STR1 Further provided are compositions and methods comprising those compounds for the control of undesirable plant species.
