62392-84-1Relevant articles and documents
Asymmetric Synthesis of Clerodane Diterpenoids: Total Synthesis of (-)-Methyl Kolavenate
Iio, Hideo,Monden, Mitsugu,Okada, Kimikazu,Tokoroyama, Takashi
, p. 358 - 359 (1987)
The asymmetric synthesis of (8R,9S,10R)-4,8,9-trimethyl-9-vinyl-Δ4-3-octalone, a versatile intermediate for the syntheses of both trans- and cis-neo-clerodane diterpenoids, has been achieved by extension of Ender's asymmetric alkylation, and its utility is exemplified by the total synthesis of (-)-methyl kolavenate, the first example of a clerodane diterpenoid in optically active form.
Theoretical and experimental study of the absolute configuration of helical structure of (2R,3S)-Rubiginone A2 analog
Zhou, Bei-Dou,Ren, Jie,Liu, Xin-Chun,Zhu, Hua-Jie
, p. 1189 - 1194 (2013/02/25)
A novel analogue of (2R,3S)-Rubiginone A2 was synthesized as a chiral helical model compound via an eight-step procedure (2.7% overall yield). Quantum methods, such as density functional theory (DFT) at different basis sets of 6-311+(d), 6-311+
Hydrolytic enantioselective protonation of cyclic dienyl esters and a β-diketone with chiral phase-transfer catalysts
Yamamoto, Eiji,Gokuden, Daichi,Nagai, Ayano,Kamachi, Takashi,Yoshizawa, Kazunari,Hamasaki, Akiyuki,Ishida, Tamao,Tokunaga, Makoto
supporting information, p. 6178 - 6181 (2013/02/25)
Hydrolytic enantioselective protonation of dienyl esters and a β-diketone catalyzed by phase-transfer catalysts are described. The latter reaction is the first example of an enantio-convergent retro-Claisen condensation. Corresponding various optically active α,β-unsaturated ketones having tertiary chiral centers adjacent to carbonyl groups were obtained in good to excellent yields and enantiomeric ratios (83-99%, up to 97.5:2.5 er).