623929-49-7

Basic information

• Product Name: {3-[3-(2-tert-butyloxycarbonylaminoethyl)thioureido]propyl}carbamic acid benzyl ester
• Synonyms: {3-[3-(2-tert-butyloxycarbonylaminoethyl)thioureido]propyl}carbamic acid benzyl ester
• CAS NO: 623929-49-7
• Molecular Weight: 410.538
• Mol File: 623929-49-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {3-[3-(2-tert-butyloxycarbonylaminoethyl)thioureido]propyl}carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {3-[3-(2-tert-butyloxycarbonylaminoethyl)thioureido]propyl}carbamic acid benzyl ester(623929-49-7)
• EPA Substance Registry System: {3-[3-(2-tert-butyloxycarbonylaminoethyl)thioureido]propyl}carbamic acid benzyl ester(623929-49-7)

Safety Data

• Hazardous Substances Data: 623929-49-7(Hazardous Substances Data)

Upstream product

• 46460-73-5 N-benzyloxycarbonyl-1,3-diaminopropane 
• 137743-46-5 2-tert-butyloxycarbonylaminoethyl isothiocyanate 

Downstream Products

• 623929-55-5 {3-[N'-(2-tert-butoxycarbonylaminoethyl)-N''-(2,2,2-trifluoroacetyl)guanidino]propyl}carbamic acid benzyl ester 

Relevant articles and documents

Trifluoroacetyl as an Orthogonal Protecting Group for Guanidines

The trifluoroacetyl moiety has been used as a new protecting group for guanidine functionality. The protecting group is easily cleaved under mild basic conditions and is complementary to the Boc, Cbz, and Ddpe protecting groups. The protecting group can be applied to peptide synthesis in solution as well as on a solid phase as it is orthogonal to a Boc and Cbz strategy and semiorthogonal to an Fmoc strategy.