625-47-8

Basic information

• Product Name: 1-Chloro-2-nitroethane
• Synonyms: 1-Chloro-2-nitroethane
• CAS NO: 625-47-8
• Molecular Formula: C₂H₄ClNO₂
• Molecular Weight: 109.5117
• Mol File: 625-47-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 173.5°C (estimate)
• Flash Point: 56.5°C
• Appearance: /
• Density: 1.3550
• Vapor Pressure: 1.26mmHg at 25°C
• Refractive Index: 1.4070 (estimate)
• CAS DataBase Reference: 1-Chloro-2-nitroethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-2-nitroethane(625-47-8)
• EPA Substance Registry System: 1-Chloro-2-nitroethane(625-47-8)

Safety Data

• Hazardous Substances Data: 625-47-8(Hazardous Substances Data)

Usage

Purification Methods

Dissolve it in alkali, extract with ether (discard), then the aqueous phase is acidified with hydroxylamine hydrochloride, and the nitro compound is collected and fractionally distilled under reduced pressure. [Pearson & Dillon J Am Chem Soc 75 2439 1953, Beilstein 1 H 101, 1 III 202, 1 IV 173.]

InChI:InChI=1/C2H4ClNO2/c3-1-2-4(5)6/h1-2H2

Upstream product

• 74-85-1 ethene 
• 75-09-2 dichloromethane 
• 79-24-3 Nitroethane 

Downstream Products

• 625-48-9 2-nitro-1-ethanol 
• 7647-01-0 hydrogenchloride 
• 3638-64-0 1-nitroethylene 
• 7803-49-8 hydroxylamine 
• 79-11-8 chloroacetic acid 
• 730971-83-2 N-(2-nitro-ethyl)-anthranilic acid 
• 768-16-1 5-Nitrobicyclo<2.2.1>hept-2-en 
• 145389-81-7 N-(4-chloro-3-sulfamoylphenyl)-2-nitroethyleneamine 
• 83600-07-1 1-nitro-2-phenylaminoethane 

Relevant articles and documents

Visible Light-Induced Oxidative Chlorination of Alkyl sp3 C-H Bonds with NaCl/Oxone at Room Temperature

A visible light-induced monochlorination of cyclohexane with sodium chloride (5:1) has been successfully accomplished to afford chlorocyclohexane in excellent yield by using Oxone as the oxidant in H2O/CF3CH2OH at room temperature. Other secondary and primary alkyl sp3 C-H bonds of cycloalkanes and functional branch/linear alkanes can also be chlorinated, respectively, under similar conditions. The selection of a suitable organic solvent is crucial in these efficient radical chlorinations of alkanes in two-phase solutions. It is studied further by the achievement of high chemoselectivity in the chlorination of the benzyl sp3 C-H bond or the aryl sp2 C-H bond of toluene.