62595-11-3Relevant articles and documents
Biosynthesis of luciferin in the sea firefly, Cypridina hilgendorfii: L-tryptophan is a component in Cypridina luciferin
Oba, Yuichi,Kato, Shin-Ichi,Ojika, Makoto,Inouye, Satoshi
, p. 2389 - 2392 (2002)
Feeding experiment to the marine ostracod crustacean, Cypridina (Vargula) hilgendorfii, using L-tryptophan labeled with deuterium at indole ring revealed that the labeled L-tryptophan was incorporated into Cypridina luciferin as a component and the animals were able to synthesize the luciferin in a de novo synthetic pathway.
Hydrogen/deuterium exchange of cross-linkable α-amino acid derivatives in deuterated triflic acid
Wang, Lei,Murai, Yuta,Yoshida, Takuma,Okamoto, Masashi,Masuda, Katsuyoshi,Sakihama, Yasuko,Hashidoko, Yasuyuki,Hatanaka, Yasumaru,Hashimoto, Makoto
, p. 1129 - 1134 (2015/07/20)
In this paper we report here a hydrogen/deuterium exchange (H/D exchange) of cross-linkable α-amino acid derivatives with deuterated trifluoromethanesulfonic acid (TfOD). H/D exchange with TfOD was easily applied to o-catechol containing phenylalanine (DOPA) within an hour. A partial H/D exchange was observed for trifluoromethyldiazirinyl (TFMD) phenylalanine derivatives. N-Acetyl-protected natural aromatic α-amino acids (Tyr and Trp) were more effective in H/D exchange than unprotected ones. The N-acetylated TFMD phenylalanine derivative afforded slightly higher H/D exchange than unprotected derivatives. An effective post-deuteration method for cross-linkable α-amino acid derivatives will be useful for the analysis of biological functions of bioactive peptides and proteins by mass spectrometry.